Candida albicans interface infection after deep anterior lamellar keratoplasty
The clinical features of interface Candida keratitis after deep anterior lamellar keratoplasty (DALK), may imitate rejection or crystalline keratopathy. We report here an 18-year-old woman presented with red eye, 4 months after undergoing DALK. Slit lamp examination revealed keratic precipitates (KP...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=4;spage=328;epage=330;aulast=Sedaghat |
| _version_ | 1818254998236037120 |
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| author | Mohammad Reza Sedaghat Setareh Sagheb Hosseinpoor |
| author_facet | Mohammad Reza Sedaghat Setareh Sagheb Hosseinpoor |
| author_sort | Mohammad Reza Sedaghat |
| collection | DOAJ |
| description | The clinical features of interface Candida keratitis after deep anterior lamellar keratoplasty (DALK), may imitate rejection or crystalline keratopathy. We report here an 18-year-old woman presented with red eye, 4 months after undergoing DALK. Slit lamp examination revealed keratic precipitates (KPs) and cojunctival injection. She was prescribed corticosteroid treatment for endothelial rejection by another ophthalmologist because of misdiagnosis, but suffered a recurrence of symptoms after reduction of the corticosteroid treatment. At that time, she was referred to our office. The recurrence persisted despite antibiotic and antifungal therapies. Ten days after treatment with interface irrigation with amphotericin, the infiltration and hypopyon were resolved. Topical steroid was added after 3 months of antifungal monotherapy. Irrigant cultures confirmed the presence of Candida albicans. The corneal graft appeared semi-clear with no signs of infection at 17-month follow-up. We recommend a close follow-up and a timely intervention to prevent the need for more invasive treatment such as penetrating keratoplasty. |
| first_indexed | 2024-12-12T17:04:52Z |
| format | Article |
| id | doaj.art-8863f142794442c8a8b381310d38341c |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-12T17:04:52Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-8863f142794442c8a8b381310d38341c2022-12-22T00:18:01ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892012-01-0160432833010.4103/0301-4738.98723Candida albicans interface infection after deep anterior lamellar keratoplastyMohammad Reza SedaghatSetareh Sagheb HosseinpoorThe clinical features of interface Candida keratitis after deep anterior lamellar keratoplasty (DALK), may imitate rejection or crystalline keratopathy. We report here an 18-year-old woman presented with red eye, 4 months after undergoing DALK. Slit lamp examination revealed keratic precipitates (KPs) and cojunctival injection. She was prescribed corticosteroid treatment for endothelial rejection by another ophthalmologist because of misdiagnosis, but suffered a recurrence of symptoms after reduction of the corticosteroid treatment. At that time, she was referred to our office. The recurrence persisted despite antibiotic and antifungal therapies. Ten days after treatment with interface irrigation with amphotericin, the infiltration and hypopyon were resolved. Topical steroid was added after 3 months of antifungal monotherapy. Irrigant cultures confirmed the presence of Candida albicans. The corneal graft appeared semi-clear with no signs of infection at 17-month follow-up. We recommend a close follow-up and a timely intervention to prevent the need for more invasive treatment such as penetrating keratoplasty.http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=4;spage=328;epage=330;aulast=SedaghatApoptosisglaucomaintraocular pressureretinal ganglion cellsretinal ischemiatumor necrosis factor-alphaBranch retinal vein occlusionlaserLucentismacular edemaMicrobial etiologymucopurulent keratitissuppurative keratitisIntraoperative application of mitomycin Cmitomycin Cpostoperative complicationspreoperative subconjunctival injectionrecurrence raterecurrent pterygiumCataractinflammationmydriasisprevention and controlsurgeryCross-cylinder techniquephotoastigmatic refractive keratectomyrefractive surgery′BARC I-125 Ocu-Prosta seeds′choroidal melanomaplaque brachytherapyretinoblastomavasoproliferative tumorsAsian IndianAmaurosisamaurosis hemianopiacapsulolenticular cataractconjunctivalenticular cataractleukomaeye lidophthalmia chronicaophthalmic purulentisInterpretationmagnetic resonance imagingorbitophthalmologyAntivascular endothelial growth factorintravitreal bevacizumabocular inflammationAcute macular neuroretinopathyoptical coherence tomographyscotomaDesferrioxamineocular toxicityoptic neuropathypigmentary retinopathyEndophthalmitisretinal vasculitisStaphylococcus epidermidiswhite-centered retinal hemorrhagesDextrocardiananophthalmossitus inversus totalisAcquired immunodeficiency syndromecerebral abscesshuman immunodeficiency virushomonymous hemianopsiainitial ophthalmic manifestationtubercular abscesstuberculosisChronic obstructive pulmonary diseaseglobe luxationspontaneousBleomycinperiocular hemangiomastreatmentCandida albicanscorneal interface infectioncorneal interface irrigationlamellar keratoplasty |
| spellingShingle | Mohammad Reza Sedaghat Setareh Sagheb Hosseinpoor Candida albicans interface infection after deep anterior lamellar keratoplasty Indian Journal of Ophthalmology Apoptosis glaucoma intraocular pressure retinal ganglion cells retinal ischemia tumor necrosis factor-alpha Branch retinal vein occlusion laser Lucentis macular edema Microbial etiology mucopurulent keratitis suppurative keratitis Intraoperative application of mitomycin C mitomycin C postoperative complications preoperative subconjunctival injection recurrence rate recurrent pterygium Cataract inflammation mydriasis prevention and control surgery Cross-cylinder technique photoastigmatic refractive keratectomy refractive surgery ′BARC I-125 Ocu-Prosta seeds′ choroidal melanoma plaque brachytherapy retinoblastoma vasoproliferative tumors Asian Indian Amaurosis amaurosis hemianopia capsulolenticular cataract conjunctiva lenticular cataract leukoma eye lid ophthalmia chronica ophthalmic purulentis Interpretation magnetic resonance imaging orbit ophthalmology Antivascular endothelial growth factor intravitreal bevacizumab ocular inflammation Acute macular neuroretinopathy optical coherence tomography scotoma Desferrioxamine ocular toxicity optic neuropathy pigmentary retinopathy Endophthalmitis retinal vasculitis Staphylococcus epidermidis white-centered retinal hemorrhages Dextrocardia nanophthalmos situs inversus totalis Acquired immunodeficiency syndrome cerebral abscess human immunodeficiency virus homonymous hemianopsia initial ophthalmic manifestation tubercular abscess tuberculosis Chronic obstructive pulmonary disease globe luxation spontaneous Bleomycin periocular hemangiomas treatment Candida albicans corneal interface infection corneal interface irrigation lamellar keratoplasty |
| title | Candida albicans interface infection after deep anterior lamellar keratoplasty |
| title_full | Candida albicans interface infection after deep anterior lamellar keratoplasty |
| title_fullStr | Candida albicans interface infection after deep anterior lamellar keratoplasty |
| title_full_unstemmed | Candida albicans interface infection after deep anterior lamellar keratoplasty |
| title_short | Candida albicans interface infection after deep anterior lamellar keratoplasty |
| title_sort | candida albicans interface infection after deep anterior lamellar keratoplasty |
| topic | Apoptosis glaucoma intraocular pressure retinal ganglion cells retinal ischemia tumor necrosis factor-alpha Branch retinal vein occlusion laser Lucentis macular edema Microbial etiology mucopurulent keratitis suppurative keratitis Intraoperative application of mitomycin C mitomycin C postoperative complications preoperative subconjunctival injection recurrence rate recurrent pterygium Cataract inflammation mydriasis prevention and control surgery Cross-cylinder technique photoastigmatic refractive keratectomy refractive surgery ′BARC I-125 Ocu-Prosta seeds′ choroidal melanoma plaque brachytherapy retinoblastoma vasoproliferative tumors Asian Indian Amaurosis amaurosis hemianopia capsulolenticular cataract conjunctiva lenticular cataract leukoma eye lid ophthalmia chronica ophthalmic purulentis Interpretation magnetic resonance imaging orbit ophthalmology Antivascular endothelial growth factor intravitreal bevacizumab ocular inflammation Acute macular neuroretinopathy optical coherence tomography scotoma Desferrioxamine ocular toxicity optic neuropathy pigmentary retinopathy Endophthalmitis retinal vasculitis Staphylococcus epidermidis white-centered retinal hemorrhages Dextrocardia nanophthalmos situs inversus totalis Acquired immunodeficiency syndrome cerebral abscess human immunodeficiency virus homonymous hemianopsia initial ophthalmic manifestation tubercular abscess tuberculosis Chronic obstructive pulmonary disease globe luxation spontaneous Bleomycin periocular hemangiomas treatment Candida albicans corneal interface infection corneal interface irrigation lamellar keratoplasty |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=4;spage=328;epage=330;aulast=Sedaghat |
| work_keys_str_mv | AT mohammadrezasedaghat candidaalbicansinterfaceinfectionafterdeepanteriorlamellarkeratoplasty AT setarehsaghebhosseinpoor candidaalbicansinterfaceinfectionafterdeepanteriorlamellarkeratoplasty |