Beneficial Effects of Citrus Bergamia Polyphenolic Fraction on Saline Load-Induced Injury in Primary Cerebral Endothelial Cells from the Stroke-Prone Spontaneously Hypertensive Rat Model

Beneficial Effects of Citrus Bergamia Polyphenolic Fraction on Saline Load-Induced Injury in Primary Cerebral Endothelial Cells from the Stroke-Prone Spontaneously Hypertensive Rat Model

High salt load is a known noxious stimulus for vascular cells and a risk factor for cardiovascular diseases in both animal models and humans. The stroke-prone spontaneously hypertensive rat (SHRSP) accelerates stroke predisposition upon high-salt dietary feeding. We previously demonstrated that high...

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Bibliographic Details
Main Authors: Rosita Stanzione, Maurizio Forte, Maria Cotugno, Francesca Oppedisano, Cristina Carresi, Simona Marchitti, Vincenzo Mollace, Massimo Volpe, Speranza Rubattu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Nutrients
Subjects:
salt loading
endothelial cell
oxidative stress
mitochondrial dysfunction
bergamot
polyphenols
Online Access:https://www.mdpi.com/2072-6643/15/6/1334

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