Immuno-diagnosis of Mycobacterium tuberculosis in sputum, and reduction of timelines for its positive cultures to within 3 h by pathogen-specific thymidylate kinase expression assays
Abstract Background Laboratory diagnosis of Tuberculosis (TB) is traditionally based on microscopy and or culture. Microscopy is however, only sensitive to a specified degree of bacillary load not present in HIV co-infected persons. Traditional cultures of Mycobacterium tuberculosis (M. tb), on the...
Main Authors: | Misaki Wayengera, Ivan Mwebaza, Johnson Welishe, Alice Bayiyana, David P. Kateete, Eddie Wampande, Samuel Kirimunda, Edgar Kigozi, Fred Katabazi, Carol Musubika, Samuel Kyobe, Peace Babirye, Benon Asiimwe, Moses L. Joloba |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2017-08-01
|
Series: | BMC Research Notes |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13104-017-2649-y |
Similar Items
-
Mycobacterium tuberculosis thymidylate kinase antigen assays for designating incipient, high-risk latent M.tb infection
by: Misaki Wayengera, et al.
Published: (2018-03-01) -
1-(Piperidin-3-yl)thymine amides as inhibitors of M. tuberculosis thymidylate kinase
by: Yanlin Jian, et al.
Published: (2019-01-01) -
Protein kinases as antituberculosis targets: The case of thymidylate kinases
by: Sudarkodi Sukumar, et al.
Published: (2020-03-01) -
Diagnosis of tuberculosis : Experience with use of an immunochromatographic assay in a Nigerian hospital
by: Martin E Ohanu, et al.
Published: (2004-01-01) -
In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against Mycobacterium tuberculosis
by: Venugopala KN, et al.
Published: (2020-03-01)