Cancer stem cell immunoediting by IFNγ
The secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progressio...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2023-08-01
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| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-023-06079-2 |
| _version_ | 1827859721226289152 |
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| author | Claudia Galassi Lorenzo Galluzzi |
| author_facet | Claudia Galassi Lorenzo Galluzzi |
| author_sort | Claudia Galassi |
| collection | DOAJ |
| description | The secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progression and resistance to (immuno)therapy. |
| first_indexed | 2024-03-12T13:13:32Z |
| format | Article |
| id | doaj.art-886d04fb1e92484abd687286a47b3907 |
| institution | Directory Open Access Journal |
| issn | 2041-4889 |
| language | English |
| last_indexed | 2024-03-12T13:13:32Z |
| publishDate | 2023-08-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Cell Death and Disease |
| spelling | doaj.art-886d04fb1e92484abd687286a47b39072023-08-27T11:29:58ZengNature Publishing GroupCell Death and Disease2041-48892023-08-011481310.1038/s41419-023-06079-2Cancer stem cell immunoediting by IFNγClaudia Galassi0Lorenzo Galluzzi1Department of Radiation Oncology, Weill Cornell Medical CollegeDepartment of Radiation Oncology, Weill Cornell Medical CollegeThe secretion of interferon gamma (IFNG, best known as IFNγ) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that—at least in some circumstances—IFNγ can edit the breast cancer microenvironment to promote stemness, disease progression and resistance to (immuno)therapy.https://doi.org/10.1038/s41419-023-06079-2 |
| spellingShingle | Claudia Galassi Lorenzo Galluzzi Cancer stem cell immunoediting by IFNγ Cell Death and Disease |
| title | Cancer stem cell immunoediting by IFNγ |
| title_full | Cancer stem cell immunoediting by IFNγ |
| title_fullStr | Cancer stem cell immunoediting by IFNγ |
| title_full_unstemmed | Cancer stem cell immunoediting by IFNγ |
| title_short | Cancer stem cell immunoediting by IFNγ |
| title_sort | cancer stem cell immunoediting by ifnγ |
| url | https://doi.org/10.1038/s41419-023-06079-2 |
| work_keys_str_mv | AT claudiagalassi cancerstemcellimmunoeditingbyifng AT lorenzogalluzzi cancerstemcellimmunoeditingbyifng |