Autoimmune chronic gastritis - a nosological entity or a syndrome?

In patients presenting with autoimmune CG, immunohistochemical techniques were used to identify herpes viruses in the epithelial and stromal cells of gastric mucosa (cytomegalovirus infection in 100% of patients, herpes simplex virus type 1 and 2 in 50%, a combination of two and three viruses in 72%...

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Bibliographic Details
Main Authors: T. B. Topchiy, O. N. Minushkin
Format: Article
Language:Russian
Published: Remedium Group LLC 2015-12-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/333
Description
Summary:In patients presenting with autoimmune CG, immunohistochemical techniques were used to identify herpes viruses in the epithelial and stromal cells of gastric mucosa (cytomegalovirus infection in 100% of patients, herpes simplex virus type 1 and 2 in 50%, a combination of two and three viruses in 72% of patients). There is an inverse association between herpes viruses and HP: the higher is the HP concentration in the gastric mucosa, the less is the number of cells containing herpesviruses, and vice versa. A prospective five-year follow-up included 45 patients with autoimmune CG either associated or not associated with HP, of which 27 patients had ACG. Novobismol for the treatment of patients with autoimmune CG demonstrated positive clinical, endoscopic and morphological changes: the incidence and severity of dyspepsia symptoms as well as inflammation of the stomach was reduced.
ISSN:2079-701X
2658-5790