Autoimmune chronic gastritis - a nosological entity or a syndrome?

In patients presenting with autoimmune CG, immunohistochemical techniques were used to identify herpes viruses in the epithelial and stromal cells of gastric mucosa (cytomegalovirus infection in 100% of patients, herpes simplex virus type 1 and 2 in 50%, a combination of two and three viruses in 72%...

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Main Authors: T. B. Topchiy, O. N. Minushkin
Format: Article
Language:Russian
Published: Remedium Group LLC 2015-12-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/333
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author T. B. Topchiy
O. N. Minushkin
author_facet T. B. Topchiy
O. N. Minushkin
author_sort T. B. Topchiy
collection DOAJ
description In patients presenting with autoimmune CG, immunohistochemical techniques were used to identify herpes viruses in the epithelial and stromal cells of gastric mucosa (cytomegalovirus infection in 100% of patients, herpes simplex virus type 1 and 2 in 50%, a combination of two and three viruses in 72% of patients). There is an inverse association between herpes viruses and HP: the higher is the HP concentration in the gastric mucosa, the less is the number of cells containing herpesviruses, and vice versa. A prospective five-year follow-up included 45 patients with autoimmune CG either associated or not associated with HP, of which 27 patients had ACG. Novobismol for the treatment of patients with autoimmune CG demonstrated positive clinical, endoscopic and morphological changes: the incidence and severity of dyspepsia symptoms as well as inflammation of the stomach was reduced.
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spelling doaj.art-886fff9c5ea44601b80e7886a64182f62023-04-23T06:56:47ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902015-12-01013384510.21518/2079-701X-2015-13-38-45333Autoimmune chronic gastritis - a nosological entity or a syndrome?T. B. Topchiy0O. N. Minushkin1Teaching and Research Medical Center of the Russian Federation Presidential AdministrationTeaching and Research Medical Center of the Russian Federation Presidential AdministrationIn patients presenting with autoimmune CG, immunohistochemical techniques were used to identify herpes viruses in the epithelial and stromal cells of gastric mucosa (cytomegalovirus infection in 100% of patients, herpes simplex virus type 1 and 2 in 50%, a combination of two and three viruses in 72% of patients). There is an inverse association between herpes viruses and HP: the higher is the HP concentration in the gastric mucosa, the less is the number of cells containing herpesviruses, and vice versa. A prospective five-year follow-up included 45 patients with autoimmune CG either associated or not associated with HP, of which 27 patients had ACG. Novobismol for the treatment of patients with autoimmune CG demonstrated positive clinical, endoscopic and morphological changes: the incidence and severity of dyspepsia symptoms as well as inflammation of the stomach was reduced.https://www.med-sovet.pro/jour/article/view/333аутоиммунный хронический гастритантитела к париетальным клеткам желудка висмута трикалия дицитратautoimmune chronic gastritisantibodies to parietal cells of the stomachbismuth tripotassium dicitrate
spellingShingle T. B. Topchiy
O. N. Minushkin
Autoimmune chronic gastritis - a nosological entity or a syndrome?
Медицинский совет
аутоиммунный хронический гастрит
антитела к париетальным клеткам желудка висмута трикалия дицитрат
autoimmune chronic gastritis
antibodies to parietal cells of the stomach
bismuth tripotassium dicitrate
title Autoimmune chronic gastritis - a nosological entity or a syndrome?
title_full Autoimmune chronic gastritis - a nosological entity or a syndrome?
title_fullStr Autoimmune chronic gastritis - a nosological entity or a syndrome?
title_full_unstemmed Autoimmune chronic gastritis - a nosological entity or a syndrome?
title_short Autoimmune chronic gastritis - a nosological entity or a syndrome?
title_sort autoimmune chronic gastritis a nosological entity or a syndrome
topic аутоиммунный хронический гастрит
антитела к париетальным клеткам желудка висмута трикалия дицитрат
autoimmune chronic gastritis
antibodies to parietal cells of the stomach
bismuth tripotassium dicitrate
url https://www.med-sovet.pro/jour/article/view/333
work_keys_str_mv AT tbtopchiy autoimmunechronicgastritisanosologicalentityorasyndrome
AT onminushkin autoimmunechronicgastritisanosologicalentityorasyndrome