Rational design of potent ultrashort antimicrobial peptides with programmable assembly into nanostructured hydrogels

Rational design of potent ultrashort antimicrobial peptides with programmable assembly into nanostructured hydrogels

Microbial resistance to common antibiotics is threatening to cause the next pandemic crisis. In this context, antimicrobial peptides (AMPs) are receiving increased attention as an alternative approach to the traditional small molecule antibiotics. Here, we report the bi-functional rational design of...

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Bibliographic Details
Main Authors: Priscila Cardoso, Samuel Appiah Danso, Andrew Hung, Chaitali Dekiwadia, Nimish Pradhan, Jamie Strachan, Brody McDonald, Kate Firipis, Jacinta F. White, Arturo Aburto-Medina, Charlotte E. Conn, Céline Valéry
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Chemistry
Subjects:
antimicrobial peptide (AMP)
peptide hydrogels
molecular engineering
molecular self assembly
fmoc-peptides
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.1009468/full

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