Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease
Patients treated with haematopoietic stem cell transplantation are at increased risk of cutaneous malignant neoplasms. There are no reports on the characteristics of melanocytic lesions in patients with chronic graft versus host disease and the value of recognizing these difficult lesions in high-ri...
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| Format: | Article |
| Language: | English |
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Medical Journals Sweden
2019-05-01
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| Series: | Acta Dermato-Venereologica |
| Subjects: | |
| Online Access: |
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3194
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| _version_ | 1819289423216377856 |
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| author | Alicia Barreiro-Capurro José Manuel Mascaró Beatriz Alejo Galindo Priscila Giavedoni Cristina Carrera Llucia Alos Susana Puig Josep Malvehy |
| author_facet | Alicia Barreiro-Capurro José Manuel Mascaró Beatriz Alejo Galindo Priscila Giavedoni Cristina Carrera Llucia Alos Susana Puig Josep Malvehy |
| author_sort | Alicia Barreiro-Capurro |
| collection | DOAJ |
| description | Patients treated with haematopoietic stem cell transplantation are at increased risk of cutaneous malignant neoplasms. There are no reports on the characteristics of melanocytic lesions in patients with chronic graft versus host disease and the value of recognizing these difficult lesions in high-risk patients. The objective of this study is to describe the clinical and dermoscopic characteristics of melanocytic lesions in patients with chronic graft versus host disease in order to understand their morphology. A prospective cross-sectional study was performed; 10 melanocytic lesions on the trunk and extremities were selected from each patient. A statistically significant association was found between regression and high total dermoscopic score and 7-point checklist score. Lesions were excised or included in short-term digital follow-up. Melanocytic lesions in patients with chronic graft versus host disease developing after allogeneic-haematopoietic stem cell transplantation exhibit marked structural and colour changes similar to melanoma. This is believed to result from the inflammatory process associated with graft versus host disease. |
| first_indexed | 2024-12-24T03:06:37Z |
| format | Article |
| id | doaj.art-8872fa213bbc4b9bab265ac7a4db159c |
| institution | Directory Open Access Journal |
| issn | 0001-5555 1651-2057 |
| language | English |
| last_indexed | 2024-12-24T03:06:37Z |
| publishDate | 2019-05-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Acta Dermato-Venereologica |
| spelling | doaj.art-8872fa213bbc4b9bab265ac7a4db159c2022-12-21T17:18:00ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572019-05-0199977778210.2340/00015555-31945461Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host DiseaseAlicia Barreiro-Capurro0José Manuel MascaróBeatriz Alejo GalindoPriscila GiavedoniCristina CarreraLlucia AlosSusana PuigJosep Malvehy Department of Dermatology, Hospital Clínic de Barcelona, IDIBAPS, ES-08036 Barcelona, Spain. Patients treated with haematopoietic stem cell transplantation are at increased risk of cutaneous malignant neoplasms. There are no reports on the characteristics of melanocytic lesions in patients with chronic graft versus host disease and the value of recognizing these difficult lesions in high-risk patients. The objective of this study is to describe the clinical and dermoscopic characteristics of melanocytic lesions in patients with chronic graft versus host disease in order to understand their morphology. A prospective cross-sectional study was performed; 10 melanocytic lesions on the trunk and extremities were selected from each patient. A statistically significant association was found between regression and high total dermoscopic score and 7-point checklist score. Lesions were excised or included in short-term digital follow-up. Melanocytic lesions in patients with chronic graft versus host disease developing after allogeneic-haematopoietic stem cell transplantation exhibit marked structural and colour changes similar to melanoma. This is believed to result from the inflammatory process associated with graft versus host disease. https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3194 chronic graft versus host disease naevi dermoscopy digital follow-up melanoma |
| spellingShingle | Alicia Barreiro-Capurro José Manuel Mascaró Beatriz Alejo Galindo Priscila Giavedoni Cristina Carrera Llucia Alos Susana Puig Josep Malvehy Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease Acta Dermato-Venereologica chronic graft versus host disease naevi dermoscopy digital follow-up melanoma |
| title | Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease |
| title_full | Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease |
| title_fullStr | Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease |
| title_full_unstemmed | Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease |
| title_short | Clinical and Dermoscopic Evaluation of Melanocytic Lesions in Patients with Chronic Graft Versus Host Disease |
| title_sort | clinical and dermoscopic evaluation of melanocytic lesions in patients with chronic graft versus host disease |
| topic | chronic graft versus host disease naevi dermoscopy digital follow-up melanoma |
| url |
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3194
|
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