Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report
Abstract Background Sarcoidosis is a granulomatous disease predominant in women and black men that has inflammatory origin of unknown etiology; neurosarcoidosis is a rare and critical presentation of the disease. Case description A 26-year-old black female presented frontal...
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2017-08-01
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| Series: | Brazilian Neurosurgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1606290 |
| _version_ | 1819275240339931136 |
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| author | Maick Wilen Fernandes Neves Paulo Henrique Pires de Aguiar Telmo Augusto Barba Belsuzarri Wolnei Marques Zeviani João Flavio de Araújo Mattos Juliano Nery Navarro Renata de Melo Braga Marques Letícia Marissol de Souza Francisco |
| author_facet | Maick Wilen Fernandes Neves Paulo Henrique Pires de Aguiar Telmo Augusto Barba Belsuzarri Wolnei Marques Zeviani João Flavio de Araújo Mattos Juliano Nery Navarro Renata de Melo Braga Marques Letícia Marissol de Souza Francisco |
| author_sort | Maick Wilen Fernandes Neves |
| collection | DOAJ |
| description | Abstract
Background Sarcoidosis is a granulomatous disease predominant in women and black men that has inflammatory origin of unknown etiology; neurosarcoidosis is a rare and critical presentation of the disease.
Case description A 26-year-old black female presented frontal headache for 1 year, as well as behavioral and mood changes for 15 days. Skull tomography and nuclear magnetic imaging of the skull revealed damaged meninges, a right frontal bone lesion, and an intraparenchymal contrast-enhancing lesion. Screening with computed tomography (CT) scans was performed, and it showed signs of bronchiectasis in the lower third of the right lung, but it was asymptomatic. The biopsy showed signs of reactional lesion with the presence of non-caseating granulomas. After the treatment with corticosteroids, the patient presented progressive improvement.
Conclusions Neurosarcoidosis is a rare and critical pathology of sarcoidosis that presents a lytic bone lesion and clinical psychiatric symptoms; neurosarcoidosis is also rare in the literature. |
| first_indexed | 2024-12-23T23:21:11Z |
| format | Article |
| id | doaj.art-8879419087f34128b757dd6624bf51ee |
| institution | Directory Open Access Journal |
| issn | 0103-5355 2359-5922 |
| language | English |
| last_indexed | 2024-12-23T23:21:11Z |
| publishDate | 2017-08-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | Brazilian Neurosurgery |
| spelling | doaj.art-8879419087f34128b757dd6624bf51ee2022-12-21T17:26:20ZengThieme Revinter Publicações Ltda.Brazilian Neurosurgery0103-53552359-59222017-08-01360318518910.1055/s-0037-1606290Neurosarcoidosis Associated with Psychiatric Symptoms: Case ReportMaick Wilen Fernandes Neves0Paulo Henrique Pires de Aguiar1Telmo Augusto Barba Belsuzarri2Wolnei Marques Zeviani3João Flavio de Araújo Mattos4Juliano Nery Navarro5Renata de Melo Braga Marques6Letícia Marissol de Souza Francisco7Pontifícia Universidade Católica de Campinas (PUC-Campinas), Campinas, São Paulo, BrazilDepartment of Neurosurgery, Hospital Santa Paula, São Paulo, São Paulo, BrazilDepartment of Neurosurgery, Hospital Celso Pierro, PUC Campinas, Campinas, São Paulo, BrazilDepartment of Neurosurgery, Hospital Celso Pierro, PUC Campinas, Campinas, São Paulo, BrazilDepartment of Neurosurgery, Hospital Celso Pierro, PUC Campinas, Campinas, São Paulo, BrazilDepartment of Neurosurgery, Hospital Celso Pierro, PUC Campinas, Campinas, São Paulo, BrazilHospital Celso Pierro, Pontifícia Universidade Católica de Campinas (PUC-Campinas), Campinas, São Paulo, BrazilHospital Celso Pierro, Pontifícia Universidade Católica de Campinas (PUC-Campinas), Campinas, São Paulo, BrazilAbstract Background Sarcoidosis is a granulomatous disease predominant in women and black men that has inflammatory origin of unknown etiology; neurosarcoidosis is a rare and critical presentation of the disease. Case description A 26-year-old black female presented frontal headache for 1 year, as well as behavioral and mood changes for 15 days. Skull tomography and nuclear magnetic imaging of the skull revealed damaged meninges, a right frontal bone lesion, and an intraparenchymal contrast-enhancing lesion. Screening with computed tomography (CT) scans was performed, and it showed signs of bronchiectasis in the lower third of the right lung, but it was asymptomatic. The biopsy showed signs of reactional lesion with the presence of non-caseating granulomas. After the treatment with corticosteroids, the patient presented progressive improvement. Conclusions Neurosarcoidosis is a rare and critical pathology of sarcoidosis that presents a lytic bone lesion and clinical psychiatric symptoms; neurosarcoidosis is also rare in the literature.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1606290sarcoidosisneurosarcoidosispsychiatric manifestationspathology |
| spellingShingle | Maick Wilen Fernandes Neves Paulo Henrique Pires de Aguiar Telmo Augusto Barba Belsuzarri Wolnei Marques Zeviani João Flavio de Araújo Mattos Juliano Nery Navarro Renata de Melo Braga Marques Letícia Marissol de Souza Francisco Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report Brazilian Neurosurgery sarcoidosis neurosarcoidosis psychiatric manifestations pathology |
| title | Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report |
| title_full | Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report |
| title_fullStr | Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report |
| title_full_unstemmed | Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report |
| title_short | Neurosarcoidosis Associated with Psychiatric Symptoms: Case Report |
| title_sort | neurosarcoidosis associated with psychiatric symptoms case report |
| topic | sarcoidosis neurosarcoidosis psychiatric manifestations pathology |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1606290 |
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