The Effects of Barbed Repositioning Pharyngoplasty in Positional and Non-Positional OSA Patients: A Retrospective Analysis
PURPOSE: The aim of our retrospective study is evaluating the effectiveness of barbed repositioning pharyngoplasty (BRP) in a consecutive cohort of patients and assessing its impact on positional indexes in order to potentially identify specific obstructive sleep apnea (OSA) phenotypes for patients...
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MDPI AG
2022-11-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/22/6749 |
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| author | Giovanni Cammaroto Claudio Moretti Giuseppe Di Prinzio Isotta Campomagnani Giannicola Iannella Angelo Cannavicci Giuseppe Meccariello Andrea De Vito Antonino Maniaci Jerome Renè Lechien Carlos Chiesa-Estomba Christian Calvo-Henriquez Paula Martinez Ruiz de Apodaca Marina Carrasco Llatas Ahmed Yassin Bahgat Guillermo Plaza Carlos O’Connor-Reina Luca Cerritelli Virginia Corazzi Chiara Bianchini Andrea Ciorba Stefano Pelucchi Claudio Vicini |
| author_facet | Giovanni Cammaroto Claudio Moretti Giuseppe Di Prinzio Isotta Campomagnani Giannicola Iannella Angelo Cannavicci Giuseppe Meccariello Andrea De Vito Antonino Maniaci Jerome Renè Lechien Carlos Chiesa-Estomba Christian Calvo-Henriquez Paula Martinez Ruiz de Apodaca Marina Carrasco Llatas Ahmed Yassin Bahgat Guillermo Plaza Carlos O’Connor-Reina Luca Cerritelli Virginia Corazzi Chiara Bianchini Andrea Ciorba Stefano Pelucchi Claudio Vicini |
| author_sort | Giovanni Cammaroto |
| collection | DOAJ |
| description | PURPOSE: The aim of our retrospective study is evaluating the effectiveness of barbed repositioning pharyngoplasty (BRP) in a consecutive cohort of patients and assessing its impact on positional indexes in order to potentially identify specific obstructive sleep apnea (OSA) phenotypes for patients who might benefit more significantly from this intervention. METHODS: A single-center retrospective study with baseline and follow-up type III sleep tests evaluating the Apnea Hypopnea Index (AHI), supine AHI, non-supine AHI, oxygen desaturation index (ODI), mean SaO2, percentage of time spent at SaO2 below 90% (CT90), and lowest oxygen saturation (LOS) were performed. The patients were then divided into groups according to Sher’s criteria and Amsterdam Positional OSA Classification (APOC). Parametric and non-parametric tests and univariate and multivariate analyses were conducted. RESULTS: The study finally included 47 patients. The statistical analysis showed significant improvement in AHI, supine AHI, non-supine AHI, and ODI after surgery. The linear regression showed that high values of baseline AHI, AHI supine, and AHI non supine predict more significant postoperative reductions in AHI, AHI supine, and AHI non supine, respectively. Therapeutic success was achieved in 22 patients out of 47. The logistic regression did not find any independent risk factors for success. The most significant reduction in AHI, supine AHI, and non-supine AHI was observed in the APOC 3 group while the APOC 1 patients experience a substantially lower improvement. CONCLUSIONS: BRP appears to be an effective surgical procedure for the treatment of OSA. The non-positional patients might benefit more from BRP in comparison with positional patients. Moreover, OSA severity should not be considered an absolute contra-indication for this surgical procedure. |
| first_indexed | 2024-03-09T18:14:50Z |
| format | Article |
| id | doaj.art-8879566cc8164e35b64910b312193980 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T18:14:50Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-8879566cc8164e35b64910b3121939802023-11-24T08:49:29ZengMDPI AGJournal of Clinical Medicine2077-03832022-11-011122674910.3390/jcm11226749The Effects of Barbed Repositioning Pharyngoplasty in Positional and Non-Positional OSA Patients: A Retrospective AnalysisGiovanni Cammaroto0Claudio Moretti1Giuseppe Di Prinzio2Isotta Campomagnani3Giannicola Iannella4Angelo Cannavicci5Giuseppe Meccariello6Andrea De Vito7Antonino Maniaci8Jerome Renè Lechien9Carlos Chiesa-Estomba10Christian Calvo-Henriquez11Paula Martinez Ruiz de Apodaca12Marina Carrasco Llatas13Ahmed Yassin Bahgat14Guillermo Plaza15Carlos O’Connor-Reina16Luca Cerritelli17Virginia Corazzi18Chiara Bianchini19Andrea Ciorba20Stefano Pelucchi21Claudio Vicini22Ent Department, Morgagni Pierantoni Hospital, 47121 Forlì, ItalyEnt Department, University of Ferrara, 44121 Ferrara, ItalyEnt Department, University of Ferrara, 44121 Ferrara, ItalyEnt Department, University of Ferrara, 44121 Ferrara, ItalySleep Surgery Group, Young-Otolaryngologists of the International Federations of Otorhino-Laryngological Societies (YO-IFOS), 13005 Marseille, FranceEnt Department, Morgagni Pierantoni Hospital, 47121 Forlì, ItalyEnt Department, Morgagni Pierantoni Hospital, 47121 Forlì, ItalyOtolaryngology and Head-Neck Surgery Unit, Department of Head-Neck Surgeries, Santa Maria delle Croci, Azienda USL della Romagna, 48121 Ravenna, ItalyDepartment of Medical, Surgical and Advanced Technologies G.F. Ingrassia, ENT Section, University of Catania, Via Santa Sofia, 95100 Catania, ItalySleep Surgery Group, Young-Otolaryngologists of the International Federations of Otorhino-Laryngological Societies (YO-IFOS), 13005 Marseille, FranceSleep Surgery Group, Young-Otolaryngologists of the International Federations of Otorhino-Laryngological Societies (YO-IFOS), 13005 Marseille, FranceSleep Surgery Group, Young-Otolaryngologists of the International Federations of Otorhino-Laryngological Societies (YO-IFOS), 13005 Marseille, FranceSleep Surgery Group, Young-Otolaryngologists of the International Federations of Otorhino-Laryngological Societies (YO-IFOS), 13005 Marseille, FranceDepartment of Otorhinolaryngology, Dr. Peset University Hospital, 46017 Valencia, SpainDepartment of Otorhinolaryngology, Alexandria University, Alexandria 21928, EgyptOtorhinolaryngology Department, Hospital Universitario de Fuenlabrada and Hospital Sanitas la Zarzuela, Universidad Rey Juan Carlos, 28042 Madrid, SpainDepartment of Otorhinolaryngology, Hospital Quironsalud Marbella, 29603 Marbella, SpainEnt Department, University of Ferrara, 44121 Ferrara, ItalyEnt Department, University of Ferrara, 44121 Ferrara, ItalyEnt Department, University of Ferrara, 44121 Ferrara, ItalyEnt Department, University of Ferrara, 44121 Ferrara, ItalyEnt Department, University of Ferrara, 44121 Ferrara, ItalyEnt Department, Morgagni Pierantoni Hospital, 47121 Forlì, ItalyPURPOSE: The aim of our retrospective study is evaluating the effectiveness of barbed repositioning pharyngoplasty (BRP) in a consecutive cohort of patients and assessing its impact on positional indexes in order to potentially identify specific obstructive sleep apnea (OSA) phenotypes for patients who might benefit more significantly from this intervention. METHODS: A single-center retrospective study with baseline and follow-up type III sleep tests evaluating the Apnea Hypopnea Index (AHI), supine AHI, non-supine AHI, oxygen desaturation index (ODI), mean SaO2, percentage of time spent at SaO2 below 90% (CT90), and lowest oxygen saturation (LOS) were performed. The patients were then divided into groups according to Sher’s criteria and Amsterdam Positional OSA Classification (APOC). Parametric and non-parametric tests and univariate and multivariate analyses were conducted. RESULTS: The study finally included 47 patients. The statistical analysis showed significant improvement in AHI, supine AHI, non-supine AHI, and ODI after surgery. The linear regression showed that high values of baseline AHI, AHI supine, and AHI non supine predict more significant postoperative reductions in AHI, AHI supine, and AHI non supine, respectively. Therapeutic success was achieved in 22 patients out of 47. The logistic regression did not find any independent risk factors for success. The most significant reduction in AHI, supine AHI, and non-supine AHI was observed in the APOC 3 group while the APOC 1 patients experience a substantially lower improvement. CONCLUSIONS: BRP appears to be an effective surgical procedure for the treatment of OSA. The non-positional patients might benefit more from BRP in comparison with positional patients. Moreover, OSA severity should not be considered an absolute contra-indication for this surgical procedure.https://www.mdpi.com/2077-0383/11/22/6749OSApharyngoplastypositional OSAsleep surgery |
| spellingShingle | Giovanni Cammaroto Claudio Moretti Giuseppe Di Prinzio Isotta Campomagnani Giannicola Iannella Angelo Cannavicci Giuseppe Meccariello Andrea De Vito Antonino Maniaci Jerome Renè Lechien Carlos Chiesa-Estomba Christian Calvo-Henriquez Paula Martinez Ruiz de Apodaca Marina Carrasco Llatas Ahmed Yassin Bahgat Guillermo Plaza Carlos O’Connor-Reina Luca Cerritelli Virginia Corazzi Chiara Bianchini Andrea Ciorba Stefano Pelucchi Claudio Vicini The Effects of Barbed Repositioning Pharyngoplasty in Positional and Non-Positional OSA Patients: A Retrospective Analysis Journal of Clinical Medicine OSA pharyngoplasty positional OSA sleep surgery |
| title | The Effects of Barbed Repositioning Pharyngoplasty in Positional and Non-Positional OSA Patients: A Retrospective Analysis |
| title_full | The Effects of Barbed Repositioning Pharyngoplasty in Positional and Non-Positional OSA Patients: A Retrospective Analysis |
| title_fullStr | The Effects of Barbed Repositioning Pharyngoplasty in Positional and Non-Positional OSA Patients: A Retrospective Analysis |
| title_full_unstemmed | The Effects of Barbed Repositioning Pharyngoplasty in Positional and Non-Positional OSA Patients: A Retrospective Analysis |
| title_short | The Effects of Barbed Repositioning Pharyngoplasty in Positional and Non-Positional OSA Patients: A Retrospective Analysis |
| title_sort | effects of barbed repositioning pharyngoplasty in positional and non positional osa patients a retrospective analysis |
| topic | OSA pharyngoplasty positional OSA sleep surgery |
| url | https://www.mdpi.com/2077-0383/11/22/6749 |
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