Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocol
IntroductionThe use of new technologies presents an opportunity to promote physical activity, especially among young people with type 1 diabetes (T1DM), who tend to be less active compared to their healthy counterparts. The aim of this study is to investigate the impact of a personalized resistance...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-02-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2024.1354734/full |
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| author | Ignacio Hormazábal-Aguayo Jacinto Muñoz-Pardeza José Francisco López-Gil Nidia Huerta-Uribe María J. Chueca-Guindulain Sara Berrade-Zubiri Elisabet Burillo Sánchez Mikel Izquierdo Yasmin Ezzatvar Antonio García-Hermoso |
| author_facet | Ignacio Hormazábal-Aguayo Jacinto Muñoz-Pardeza José Francisco López-Gil Nidia Huerta-Uribe María J. Chueca-Guindulain Sara Berrade-Zubiri Elisabet Burillo Sánchez Mikel Izquierdo Yasmin Ezzatvar Antonio García-Hermoso |
| author_sort | Ignacio Hormazábal-Aguayo |
| collection | DOAJ |
| description | IntroductionThe use of new technologies presents an opportunity to promote physical activity, especially among young people with type 1 diabetes (T1DM), who tend to be less active compared to their healthy counterparts. The aim of this study is to investigate the impact of a personalized resistance exercise program, facilitated by the Diactive-1 App, on insulin requirements among children and adolescents diagnosed with T1DM.Methods and analysisA minimum of 52 children and adolescents aged 8-18 years, who were diagnosed with T1DM at least 6 months ago, will be randomly assigned to either a group engaging in an individualized resistance exercise program at least 3 times per week over a 24-week period or a waiting-list control group. The primary outcome will be the daily insulin dose requirement. The secondary outcomes will include glycemic control, cardiometabolic profile, body composition, vascular function, physical fitness, 24-hour movement behaviors, diet, and psychological parameters. The usability of the app will also be assessed.Ethics and disseminationEthical approval to conduct this study has been granted by the University Hospital of Navarra Research Board (PI_2020/140). Parents or legal guardians of minors participating in the study will provide written consent, while children and adolescents will sign an assent form to indicate their voluntary agreement. The trial’s main findings will be shared through conference presentations, peer-reviewed publications, and communication directly with participating families. This study aims to offer valuable insights into the holistic management of children and adolescents with T1DM by utilizing personalized exercise interventions through an mHealth system.Trial registrationNCT06048757 |
| first_indexed | 2024-03-08T05:31:06Z |
| format | Article |
| id | doaj.art-887cc059e46b48c6a4c12cc3e9f2bc9e |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-08T05:31:06Z |
| publishDate | 2024-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-887cc059e46b48c6a4c12cc3e9f2bc9e2024-02-06T05:02:37ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922024-02-011510.3389/fendo.2024.13547341354734Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocolIgnacio Hormazábal-Aguayo0Jacinto Muñoz-Pardeza1José Francisco López-Gil2Nidia Huerta-Uribe3María J. Chueca-Guindulain4Sara Berrade-Zubiri5Elisabet Burillo Sánchez6Mikel Izquierdo7Yasmin Ezzatvar8Antonio García-Hermoso9Navarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, SpainNavarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, SpainOne Health Research Group, Universidad de Las Américas, Quito, EcuadorNavarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, SpainPediatric Endocrinology Unit, Hospital Universitario de Navarra (HUN), IdiSNA, Pamplona, SpainPediatric Endocrinology Unit, Hospital Universitario de Navarra (HUN), IdiSNA, Pamplona, SpainPediatric Endocrinology Unit, Hospital Universitario de Navarra (HUN), IdiSNA, Pamplona, SpainNavarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, SpainDepartment of Nursing, Universitat de València, Valencia, SpainNavarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA, Pamplona, SpainIntroductionThe use of new technologies presents an opportunity to promote physical activity, especially among young people with type 1 diabetes (T1DM), who tend to be less active compared to their healthy counterparts. The aim of this study is to investigate the impact of a personalized resistance exercise program, facilitated by the Diactive-1 App, on insulin requirements among children and adolescents diagnosed with T1DM.Methods and analysisA minimum of 52 children and adolescents aged 8-18 years, who were diagnosed with T1DM at least 6 months ago, will be randomly assigned to either a group engaging in an individualized resistance exercise program at least 3 times per week over a 24-week period or a waiting-list control group. The primary outcome will be the daily insulin dose requirement. The secondary outcomes will include glycemic control, cardiometabolic profile, body composition, vascular function, physical fitness, 24-hour movement behaviors, diet, and psychological parameters. The usability of the app will also be assessed.Ethics and disseminationEthical approval to conduct this study has been granted by the University Hospital of Navarra Research Board (PI_2020/140). Parents or legal guardians of minors participating in the study will provide written consent, while children and adolescents will sign an assent form to indicate their voluntary agreement. The trial’s main findings will be shared through conference presentations, peer-reviewed publications, and communication directly with participating families. This study aims to offer valuable insights into the holistic management of children and adolescents with T1DM by utilizing personalized exercise interventions through an mHealth system.Trial registrationNCT06048757https://www.frontiersin.org/articles/10.3389/fendo.2024.1354734/fullinsulin-dependent diabetes mellitusphysical exerciseresistance trainingmobile-healthpediatrics |
| spellingShingle | Ignacio Hormazábal-Aguayo Jacinto Muñoz-Pardeza José Francisco López-Gil Nidia Huerta-Uribe María J. Chueca-Guindulain Sara Berrade-Zubiri Elisabet Burillo Sánchez Mikel Izquierdo Yasmin Ezzatvar Antonio García-Hermoso Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocol Frontiers in Endocrinology insulin-dependent diabetes mellitus physical exercise resistance training mobile-health pediatrics |
| title | Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocol |
| title_full | Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocol |
| title_fullStr | Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocol |
| title_full_unstemmed | Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocol |
| title_short | Comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mHealth system: The Diactive-1 study protocol |
| title_sort | comprehensive management of children and adolescents with type 1 diabetes mellitus through personalized physical exercise and education using an mhealth system the diactive 1 study protocol |
| topic | insulin-dependent diabetes mellitus physical exercise resistance training mobile-health pediatrics |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2024.1354734/full |
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