Determining Antigen Specificity of Human Islet Infiltrating T Cells in Type 1 Diabetes

Determining Antigen Specificity of Human Islet Infiltrating T Cells in Type 1 Diabetes

Type 1 diabetes, the immune mediated form of diabetes, represents a prototypical organ specific autoimmune disease in that insulin producing pancreatic islets are specifically targeted by T cells. The disease is now predictable in humans with the measurement of type 1 diabetes associated autoantibod...

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Bibliographic Details
Main Authors: Maki Nakayama, Aaron W. Michels
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
diabetes
autoimmunity
HLA
insulin
T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00365/full

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