Hamman-Rich syndrome
Introduction: Acute interstitial pneumonia is a rare but important diagnosis, associated with a high mortality rate and important to identify early.Case presentation: A 76 year-old individual presented to hospital with a two-week history of shortness of breath, fevers and a non-productive cough.Trea...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-01-01
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| Series: | Respiratory Medicine Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007117302368 |
| _version_ | 1811270681674907648 |
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| author | Arshiya Mastan Nilaani Murugesu Adil Hasnain Terry O'Shaughnessy Vladimir Macavei |
| author_facet | Arshiya Mastan Nilaani Murugesu Adil Hasnain Terry O'Shaughnessy Vladimir Macavei |
| author_sort | Arshiya Mastan |
| collection | DOAJ |
| description | Introduction: Acute interstitial pneumonia is a rare but important diagnosis, associated with a high mortality rate and important to identify early.Case presentation: A 76 year-old individual presented to hospital with a two-week history of shortness of breath, fevers and a non-productive cough.Treatment initially was for lower respiratory tract infection but returned to hospital three days later as her shortness of breath and peripheral oedema was worsening despite diuretic treatment. Arterial blood gas showed Type 1 Respiratory Failure (p02 was only 10 kPa on 4 L per minute of oxygen). A computed tomography pulmonary angiography (CTPA) was performed to rule out a pulmonary embolism (PE), which showed multifocal diffuse areas of consolidations bilaterally involving all lobes. Bronchoalveolar lavage cellular analysis was also done.The patient was treated as nonspecific interstitial pneumonia. This case study highlights this rare condition presenting similarly to common pulmonary conditions.Discussion: The disease is often preceded by a flu-like prodromal illness lasting one to two weeks prior to presentation. Acute respiratory failure develops in previously healthy individuals without pre-existing lung disease. Diagnosis is also supported by high-resolution computed tomography (HRCT). The effects of high flow ventilation in patients with idiopathic pulmonary fibrosis are associated with improvement in respiratory parameters, improving the efficiency of breathing.Conclusion: Acute interstitial pneumonitis can be a difficult diagnosis, associated with a high mortality rate up to 60%. It is also difficult to treat; however supportive treatment with high flow oxygen therapy along with pulsatile high dose Corticosteroids can aid recovery. |
| first_indexed | 2024-04-12T22:06:26Z |
| format | Article |
| id | doaj.art-888a972876714e6e9d1e3cdedf6d6acc |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-04-12T22:06:26Z |
| publishDate | 2018-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-888a972876714e6e9d1e3cdedf6d6acc2022-12-22T03:14:56ZengElsevierRespiratory Medicine Case Reports2213-00712018-01-01231317Hamman-Rich syndromeArshiya Mastan0Nilaani Murugesu1Adil Hasnain2Terry O'Shaughnessy3Vladimir Macavei4Corresponding author.; Respiratory Medicine Department, Newham University Hospital, Barts Health NHS Trust, London, United KingdomRespiratory Medicine Department, Newham University Hospital, Barts Health NHS Trust, London, United KingdomRespiratory Medicine Department, Newham University Hospital, Barts Health NHS Trust, London, United KingdomRespiratory Medicine Department, Newham University Hospital, Barts Health NHS Trust, London, United KingdomRespiratory Medicine Department, Newham University Hospital, Barts Health NHS Trust, London, United KingdomIntroduction: Acute interstitial pneumonia is a rare but important diagnosis, associated with a high mortality rate and important to identify early.Case presentation: A 76 year-old individual presented to hospital with a two-week history of shortness of breath, fevers and a non-productive cough.Treatment initially was for lower respiratory tract infection but returned to hospital three days later as her shortness of breath and peripheral oedema was worsening despite diuretic treatment. Arterial blood gas showed Type 1 Respiratory Failure (p02 was only 10 kPa on 4 L per minute of oxygen). A computed tomography pulmonary angiography (CTPA) was performed to rule out a pulmonary embolism (PE), which showed multifocal diffuse areas of consolidations bilaterally involving all lobes. Bronchoalveolar lavage cellular analysis was also done.The patient was treated as nonspecific interstitial pneumonia. This case study highlights this rare condition presenting similarly to common pulmonary conditions.Discussion: The disease is often preceded by a flu-like prodromal illness lasting one to two weeks prior to presentation. Acute respiratory failure develops in previously healthy individuals without pre-existing lung disease. Diagnosis is also supported by high-resolution computed tomography (HRCT). The effects of high flow ventilation in patients with idiopathic pulmonary fibrosis are associated with improvement in respiratory parameters, improving the efficiency of breathing.Conclusion: Acute interstitial pneumonitis can be a difficult diagnosis, associated with a high mortality rate up to 60%. It is also difficult to treat; however supportive treatment with high flow oxygen therapy along with pulsatile high dose Corticosteroids can aid recovery.http://www.sciencedirect.com/science/article/pii/S2213007117302368 |
| spellingShingle | Arshiya Mastan Nilaani Murugesu Adil Hasnain Terry O'Shaughnessy Vladimir Macavei Hamman-Rich syndrome Respiratory Medicine Case Reports |
| title | Hamman-Rich syndrome |
| title_full | Hamman-Rich syndrome |
| title_fullStr | Hamman-Rich syndrome |
| title_full_unstemmed | Hamman-Rich syndrome |
| title_short | Hamman-Rich syndrome |
| title_sort | hamman rich syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S2213007117302368 |
| work_keys_str_mv | AT arshiyamastan hammanrichsyndrome AT nilaanimurugesu hammanrichsyndrome AT adilhasnain hammanrichsyndrome AT terryoshaughnessy hammanrichsyndrome AT vladimirmacavei hammanrichsyndrome |