The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controls
Objectives: Cognitive deficits in Bipolar Disorder (BD) are significant enough to have an impact on daily functioning. Therefore, appropriate tools must be used to improve our understanding of the nature and severity of cognitive deficits in BD. In this study, we aimed to compare the cognitive profi...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-08-01
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| Series: | Comprehensive Psychiatry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0010440X22000414 |
| _version_ | 1828269238558654464 |
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| author | Maria Gloria Rossetti Cinzia Perlini Vera Abbiati Carolina Bonivento Elisabetta Caletti Giuseppe Fanelli Mariangela Lanfredi Matteo Lazzaretti Laura Pedrini Sara Piccin Stefano Porcelli Michela Sala Alessandro Serretti Marcella Bellani Paolo Brambilla |
| author_facet | Maria Gloria Rossetti Cinzia Perlini Vera Abbiati Carolina Bonivento Elisabetta Caletti Giuseppe Fanelli Mariangela Lanfredi Matteo Lazzaretti Laura Pedrini Sara Piccin Stefano Porcelli Michela Sala Alessandro Serretti Marcella Bellani Paolo Brambilla |
| author_sort | Maria Gloria Rossetti |
| collection | DOAJ |
| description | Objectives: Cognitive deficits in Bipolar Disorder (BD) are significant enough to have an impact on daily functioning. Therefore, appropriate tools must be used to improve our understanding of the nature and severity of cognitive deficits in BD. In this study, we aimed to compare the cognitive profiles of patients with BD and healthy controls (HC) applying the Italian version of the Brief Assessment of Cognition in Affective Disorders (BAC-A). Methods: This cross-sectional study included 127 patients with BD and 134 HC. The participants' cognitive profiles were evaluated using the Italian version of the BAC-A, which assesses verbal memory, working memory, motor speed, verbal fluency, attention & processing speed, executive functions, and two new measures of affective processing. The BAC-A raw scores were corrected using the normative data for the Italian population. In addition, we explored whether intelligence quotient (IQ) and specific clinical variables would predict the BAC-A affective, non-affective, and total composite scores of patients with BD and HC. Results: HC performed better than patients with BD in all BAC-A subtests (all p < .001), except for subtests of the Affective Interference Test. (p ≥ .05). The effect sizes varied in magnitude and ranged between d = 0.02 and d = 1.27. In patients with BD, lower BAC-A composite scores were predicted by a higher number of hospitalizations. There was a significant association between IQ and BAC-A composite scores in both bipolar patients and HC. Conclusions: The Italian BAC-A is sensitive to the cognitive impairments of patients with BD in both affective and non-affective cognitive domains. |
| first_indexed | 2024-04-13T05:28:18Z |
| format | Article |
| id | doaj.art-8894e1c412624517bef2a69b97a98251 |
| institution | Directory Open Access Journal |
| issn | 0010-440X |
| language | English |
| last_indexed | 2024-04-13T05:28:18Z |
| publishDate | 2022-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Comprehensive Psychiatry |
| spelling | doaj.art-8894e1c412624517bef2a69b97a982512022-12-22T03:00:31ZengElsevierComprehensive Psychiatry0010-440X2022-08-01117152335The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controlsMaria Gloria Rossetti0Cinzia Perlini1Vera Abbiati2Carolina Bonivento3Elisabetta Caletti4Giuseppe Fanelli5Mariangela Lanfredi6Matteo Lazzaretti7Laura Pedrini8Sara Piccin9Stefano Porcelli10Michela Sala11Alessandro Serretti12Marcella Bellani13Paolo Brambilla14Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, ItalyDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Psychology, University of Verona, Verona, ItalyDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, ItalyIRCCS ''E. Medea”, Polo Friuli Venezia Giulia, San Vito al Tagliamento (PN), ItalyDepartment of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, ItalyDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, ItalyUnit of Psychiatry, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, ItalyDepartment of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, ItalyUnit of Psychiatry, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, ItalyUnit of Psychiatry, Department of Medicine (DAME), University of Udine, Udine, ItalyDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, ItalyDepartment of Mental Health, Azienda Sanitaria Locale Alessandria, Alessandria, ItalyDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, ItalyDepartment of Neurosciences, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy; Corresponding author.Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milan, ItalyObjectives: Cognitive deficits in Bipolar Disorder (BD) are significant enough to have an impact on daily functioning. Therefore, appropriate tools must be used to improve our understanding of the nature and severity of cognitive deficits in BD. In this study, we aimed to compare the cognitive profiles of patients with BD and healthy controls (HC) applying the Italian version of the Brief Assessment of Cognition in Affective Disorders (BAC-A). Methods: This cross-sectional study included 127 patients with BD and 134 HC. The participants' cognitive profiles were evaluated using the Italian version of the BAC-A, which assesses verbal memory, working memory, motor speed, verbal fluency, attention & processing speed, executive functions, and two new measures of affective processing. The BAC-A raw scores were corrected using the normative data for the Italian population. In addition, we explored whether intelligence quotient (IQ) and specific clinical variables would predict the BAC-A affective, non-affective, and total composite scores of patients with BD and HC. Results: HC performed better than patients with BD in all BAC-A subtests (all p < .001), except for subtests of the Affective Interference Test. (p ≥ .05). The effect sizes varied in magnitude and ranged between d = 0.02 and d = 1.27. In patients with BD, lower BAC-A composite scores were predicted by a higher number of hospitalizations. There was a significant association between IQ and BAC-A composite scores in both bipolar patients and HC. Conclusions: The Italian BAC-A is sensitive to the cognitive impairments of patients with BD in both affective and non-affective cognitive domains.http://www.sciencedirect.com/science/article/pii/S0010440X22000414BAC-ABipolar disorderAffective disordersCognitiveAffective processingNeuropsychology |
| spellingShingle | Maria Gloria Rossetti Cinzia Perlini Vera Abbiati Carolina Bonivento Elisabetta Caletti Giuseppe Fanelli Mariangela Lanfredi Matteo Lazzaretti Laura Pedrini Sara Piccin Stefano Porcelli Michela Sala Alessandro Serretti Marcella Bellani Paolo Brambilla The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controls Comprehensive Psychiatry BAC-A Bipolar disorder Affective disorders Cognitive Affective processing Neuropsychology |
| title | The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controls |
| title_full | The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controls |
| title_fullStr | The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controls |
| title_full_unstemmed | The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controls |
| title_short | The Italian version of the Brief Assessment of Cognition in Affective Disorders: performance of patients with bipolar disorder and healthy controls |
| title_sort | italian version of the brief assessment of cognition in affective disorders performance of patients with bipolar disorder and healthy controls |
| topic | BAC-A Bipolar disorder Affective disorders Cognitive Affective processing Neuropsychology |
| url | http://www.sciencedirect.com/science/article/pii/S0010440X22000414 |
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