A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran
Introduction:In the present study, we evaluated the 4-year antimicrobial resistance trends of several nosocomial pathogens during 2018-2021 in a reffereal Mashhad hospital, Mashhad, Iran. Methods:In this study, we reviewed the data of 70,234 clinical isolates were registred Infection Control Data of...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mashhad University of Medical Sciences
2021-06-01
|
| Series: | Reviews in Clinical Medicine |
| Subjects: | |
| Online Access: | https://rcm.mums.ac.ir/article_18106_ec5fe916f7bbdc9c768333b39729ef3e.pdf |
| _version_ | 1819283168904085504 |
|---|---|
| author | Mahbobeh Khammar Sepideh Hassanzadeh Fatemeh Tara Malihe Siahsar Fatemeh Tahmasbi Masoud Keikha Kiarash Ghazvini |
| author_facet | Mahbobeh Khammar Sepideh Hassanzadeh Fatemeh Tara Malihe Siahsar Fatemeh Tahmasbi Masoud Keikha Kiarash Ghazvini |
| author_sort | Mahbobeh Khammar |
| collection | DOAJ |
| description | Introduction:In the present study, we evaluated the 4-year antimicrobial resistance trends of several nosocomial pathogens during 2018-2021 in a reffereal Mashhad hospital, Mashhad, Iran.
Methods:In this study, we reviewed the data of 70,234 clinical isolates were registred Infection Control Data of Ghaem Hospital, Mashhad, Iran. The antimicrobial susceptibility testing was performed using Kirby-Bauer disk diffusion method according to clinical and laboratory standard institute (CLSI) instructions to evaluate trends of antimicrobial resistance over the times.
Results: There were identified (A. baumannii: n = 19,374; K. pneumonia n = 17,206; E. coli n = 23,777; S. epidermidis: n = 9,877). We did not find any significant difference in changes of antimicrobial trends over the time except in minor cases . However, The pattern of antimicrobial drug resistance was gradually differed except E. coli.
Conclusion: our results suggested the overall antimicrobial resistance trends was remins the same level during 2018-2021. It seems that in accessibility and stop prescribing of antibiotics can lead to decreasing antibiotic resistance rate. |
| first_indexed | 2024-12-24T01:27:12Z |
| format | Article |
| id | doaj.art-88971004824941d4ad424cae7cc9001e |
| institution | Directory Open Access Journal |
| issn | 2345-6256 2345-6892 |
| language | English |
| last_indexed | 2024-12-24T01:27:12Z |
| publishDate | 2021-06-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Reviews in Clinical Medicine |
| spelling | doaj.art-88971004824941d4ad424cae7cc9001e2022-12-21T17:22:27ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922021-06-0182505510.22038/rcm.2021.57591.136718106A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, IranMahbobeh Khammar0Sepideh Hassanzadeh1Fatemeh Tara2Malihe Siahsar3Fatemeh Tahmasbi4Masoud Keikha5Kiarash Ghazvini6Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, IranAntimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, IranAntimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, IranAntimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, IranAntimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Microbiology and Virology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranIntroduction:In the present study, we evaluated the 4-year antimicrobial resistance trends of several nosocomial pathogens during 2018-2021 in a reffereal Mashhad hospital, Mashhad, Iran. Methods:In this study, we reviewed the data of 70,234 clinical isolates were registred Infection Control Data of Ghaem Hospital, Mashhad, Iran. The antimicrobial susceptibility testing was performed using Kirby-Bauer disk diffusion method according to clinical and laboratory standard institute (CLSI) instructions to evaluate trends of antimicrobial resistance over the times. Results: There were identified (A. baumannii: n = 19,374; K. pneumonia n = 17,206; E. coli n = 23,777; S. epidermidis: n = 9,877). We did not find any significant difference in changes of antimicrobial trends over the time except in minor cases . However, The pattern of antimicrobial drug resistance was gradually differed except E. coli. Conclusion: our results suggested the overall antimicrobial resistance trends was remins the same level during 2018-2021. It seems that in accessibility and stop prescribing of antibiotics can lead to decreasing antibiotic resistance rate.https://rcm.mums.ac.ir/article_18106_ec5fe916f7bbdc9c768333b39729ef3e.pdfstaphylococcus epidermidisescherichia coliklebsiella pneumoniaacinetobacter baumaniiantimicrobial resistance |
| spellingShingle | Mahbobeh Khammar Sepideh Hassanzadeh Fatemeh Tara Malihe Siahsar Fatemeh Tahmasbi Masoud Keikha Kiarash Ghazvini A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran Reviews in Clinical Medicine staphylococcus epidermidis escherichia coli klebsiella pneumonia acinetobacter baumanii antimicrobial resistance |
| title | A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran |
| title_full | A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran |
| title_fullStr | A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran |
| title_full_unstemmed | A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran |
| title_short | A 4-year Study on Antimicrobial Susceptibility Trends of Nosocomial Infections in a Mashhad Referral Hospital, Mashhad, Iran |
| title_sort | 4 year study on antimicrobial susceptibility trends of nosocomial infections in a mashhad referral hospital mashhad iran |
| topic | staphylococcus epidermidis escherichia coli klebsiella pneumonia acinetobacter baumanii antimicrobial resistance |
| url | https://rcm.mums.ac.ir/article_18106_ec5fe916f7bbdc9c768333b39729ef3e.pdf |
| work_keys_str_mv | AT mahbobehkhammar a4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT sepidehhassanzadeh a4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT fatemehtara a4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT malihesiahsar a4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT fatemehtahmasbi a4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT masoudkeikha a4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT kiarashghazvini a4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT mahbobehkhammar 4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT sepidehhassanzadeh 4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT fatemehtara 4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT malihesiahsar 4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT fatemehtahmasbi 4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT masoudkeikha 4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran AT kiarashghazvini 4yearstudyonantimicrobialsusceptibilitytrendsofnosocomialinfectionsinamashhadreferralhospitalmashhadiran |