Nutritional Influence on Epigenetic Marks and Effect on Livestock Production
Nutrition represents one of the greatest environmental determinants of an individual’s health. While nutrient quantity and quality impart direct effects, the interaction of nutrition with genetic and epigenetic modifications is often overlooked despite being shown to influence biological variation i...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-10-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00182/full |
| _version_ | 1818681553688985600 |
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| author | Brenda Murdoch Gordon Murdoch Sabrina Greenwood Stephanie McKay |
| author_facet | Brenda Murdoch Gordon Murdoch Sabrina Greenwood Stephanie McKay |
| author_sort | Brenda Murdoch |
| collection | DOAJ |
| description | Nutrition represents one of the greatest environmental determinants of an individual’s health. While nutrient quantity and quality impart direct effects, the interaction of nutrition with genetic and epigenetic modifications is often overlooked despite being shown to influence biological variation in mammals. Dissecting complex traits, such as those that are diet or nutrition related, to determine the genetic and epigenetic contributions towards a phenotype can be a formidable process. Epigenetic modifications add another layer of complexity as they do not change the DNA sequence itself but can affect transcription and are important mediators of gene expression and ensuing phenotypic variation. Altered carbohydrate metabolism and rates of fat and protein deposition resulting from diet-induced hypo- or hyper-methylation highlight the capability of nutritional epigenetics to influence livestock commodity quality and quantity. This interaction can yield either products tailored to consumer preference, such as marbling in meat cuts, or potentially increasing productivity and yield both in terms of carcass yield and/or offspring performance. Understanding how these and other desirable phenotypes result from epigenetic mechanisms will facilitate their inducible potential in livestock systems. Here, we discuss the establishment of the epigenome, examples of nutritional mediated alterations of epigenetics and epigenetic effects on livestock production. |
| first_indexed | 2024-12-17T10:04:47Z |
| format | Article |
| id | doaj.art-889a258cfcf848ff82d823b7a2325b39 |
| institution | Directory Open Access Journal |
| issn | 1664-8021 |
| language | English |
| last_indexed | 2024-12-17T10:04:47Z |
| publishDate | 2016-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Genetics |
| spelling | doaj.art-889a258cfcf848ff82d823b7a2325b392022-12-21T21:53:11ZengFrontiers Media S.A.Frontiers in Genetics1664-80212016-10-01710.3389/fgene.2016.00182207631Nutritional Influence on Epigenetic Marks and Effect on Livestock ProductionBrenda Murdoch0Gordon Murdoch1Sabrina Greenwood2Stephanie McKay3University of IdahoUniversity of IdahoUniversity of VermontUniversity of VermontNutrition represents one of the greatest environmental determinants of an individual’s health. While nutrient quantity and quality impart direct effects, the interaction of nutrition with genetic and epigenetic modifications is often overlooked despite being shown to influence biological variation in mammals. Dissecting complex traits, such as those that are diet or nutrition related, to determine the genetic and epigenetic contributions towards a phenotype can be a formidable process. Epigenetic modifications add another layer of complexity as they do not change the DNA sequence itself but can affect transcription and are important mediators of gene expression and ensuing phenotypic variation. Altered carbohydrate metabolism and rates of fat and protein deposition resulting from diet-induced hypo- or hyper-methylation highlight the capability of nutritional epigenetics to influence livestock commodity quality and quantity. This interaction can yield either products tailored to consumer preference, such as marbling in meat cuts, or potentially increasing productivity and yield both in terms of carcass yield and/or offspring performance. Understanding how these and other desirable phenotypes result from epigenetic mechanisms will facilitate their inducible potential in livestock systems. Here, we discuss the establishment of the epigenome, examples of nutritional mediated alterations of epigenetics and epigenetic effects on livestock production.http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00182/fullLivestockMethylationepigeneticsNutrientsNutritional epigenetics |
| spellingShingle | Brenda Murdoch Gordon Murdoch Sabrina Greenwood Stephanie McKay Nutritional Influence on Epigenetic Marks and Effect on Livestock Production Frontiers in Genetics Livestock Methylation epigenetics Nutrients Nutritional epigenetics |
| title | Nutritional Influence on Epigenetic Marks and Effect on Livestock Production |
| title_full | Nutritional Influence on Epigenetic Marks and Effect on Livestock Production |
| title_fullStr | Nutritional Influence on Epigenetic Marks and Effect on Livestock Production |
| title_full_unstemmed | Nutritional Influence on Epigenetic Marks and Effect on Livestock Production |
| title_short | Nutritional Influence on Epigenetic Marks and Effect on Livestock Production |
| title_sort | nutritional influence on epigenetic marks and effect on livestock production |
| topic | Livestock Methylation epigenetics Nutrients Nutritional epigenetics |
| url | http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00182/full |
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