Hybrid Nanomaterials for Cancer Immunotherapy
Abstract Nano‐immunotherapy has been recognized as a highly promising strategy for cancer treatment in recent decades, which combines nanotechnology and immunotherapy to combat against tumors. Hybrid nanomaterials consisting of at least two constituents with distinct compositions and properties, usu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-02-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202204932 |
| _version_ | 1797895087404875776 |
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| author | Jianing Li Wanyue Lu Yannan Yang Ruiqing Xiang Yun Ling Chengzhong Yu Yaming Zhou |
| author_facet | Jianing Li Wanyue Lu Yannan Yang Ruiqing Xiang Yun Ling Chengzhong Yu Yaming Zhou |
| author_sort | Jianing Li |
| collection | DOAJ |
| description | Abstract Nano‐immunotherapy has been recognized as a highly promising strategy for cancer treatment in recent decades, which combines nanotechnology and immunotherapy to combat against tumors. Hybrid nanomaterials consisting of at least two constituents with distinct compositions and properties, usually organic and inorganic, have been engineered with integrated functions and enormous potential in boosting cancer immunotherapy. This review provides a summary of hybrid nanomaterials reported for cancer immunotherapy, including nanoscale metal–organic frameworks, metal–phenolic networks, mesoporous organosilica nanoparticles, metallofullerene nanomaterials, polymer–lipid, and biomacromolecule‐based hybrid nanomaterials. The combination of immunotherapy with chemotherapy, chemodynamic therapy, radiotherapy, radiodynamic therapy, photothermal therapy, photodynamic therapy, and sonodynamic therapy based on hybrid nanomaterials is also discussed. Finally, the current challenges and the prospects for designing hybrid nanomaterials and their application in cancer immunotherapy are outlined. |
| first_indexed | 2024-04-10T07:20:53Z |
| format | Article |
| id | doaj.art-889e71f870f141d5b6a72b8883e0848a |
| institution | Directory Open Access Journal |
| issn | 2198-3844 |
| language | English |
| last_indexed | 2024-04-10T07:20:53Z |
| publishDate | 2023-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj.art-889e71f870f141d5b6a72b8883e0848a2023-02-24T12:27:40ZengWileyAdvanced Science2198-38442023-02-01106n/an/a10.1002/advs.202204932Hybrid Nanomaterials for Cancer ImmunotherapyJianing Li0Wanyue Lu1Yannan Yang2Ruiqing Xiang3Yun Ling4Chengzhong Yu5Yaming Zhou6Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of Chemistry Fudan University Shanghai 200433 ChinaShanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of Chemistry Fudan University Shanghai 200433 ChinaInstitute of Optoelectronics Fudan University Shanghai 200433 ChinaShanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of Chemistry Fudan University Shanghai 200433 ChinaShanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of Chemistry Fudan University Shanghai 200433 ChinaAustralian Institute for Bioengineering and Nanotechnology The University of Queensland St Lucia Brisbane 4072 AustraliaShanghai Key Laboratory of Molecular Catalysis and Innovative Materials Department of Chemistry Fudan University Shanghai 200433 ChinaAbstract Nano‐immunotherapy has been recognized as a highly promising strategy for cancer treatment in recent decades, which combines nanotechnology and immunotherapy to combat against tumors. Hybrid nanomaterials consisting of at least two constituents with distinct compositions and properties, usually organic and inorganic, have been engineered with integrated functions and enormous potential in boosting cancer immunotherapy. This review provides a summary of hybrid nanomaterials reported for cancer immunotherapy, including nanoscale metal–organic frameworks, metal–phenolic networks, mesoporous organosilica nanoparticles, metallofullerene nanomaterials, polymer–lipid, and biomacromolecule‐based hybrid nanomaterials. The combination of immunotherapy with chemotherapy, chemodynamic therapy, radiotherapy, radiodynamic therapy, photothermal therapy, photodynamic therapy, and sonodynamic therapy based on hybrid nanomaterials is also discussed. Finally, the current challenges and the prospects for designing hybrid nanomaterials and their application in cancer immunotherapy are outlined.https://doi.org/10.1002/advs.202204932cancer immunotherapycombinational therapyhybrid nanomaterialsimmunoadjuvantvaccine |
| spellingShingle | Jianing Li Wanyue Lu Yannan Yang Ruiqing Xiang Yun Ling Chengzhong Yu Yaming Zhou Hybrid Nanomaterials for Cancer Immunotherapy Advanced Science cancer immunotherapy combinational therapy hybrid nanomaterials immunoadjuvant vaccine |
| title | Hybrid Nanomaterials for Cancer Immunotherapy |
| title_full | Hybrid Nanomaterials for Cancer Immunotherapy |
| title_fullStr | Hybrid Nanomaterials for Cancer Immunotherapy |
| title_full_unstemmed | Hybrid Nanomaterials for Cancer Immunotherapy |
| title_short | Hybrid Nanomaterials for Cancer Immunotherapy |
| title_sort | hybrid nanomaterials for cancer immunotherapy |
| topic | cancer immunotherapy combinational therapy hybrid nanomaterials immunoadjuvant vaccine |
| url | https://doi.org/10.1002/advs.202204932 |
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