Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial

Biomarkers of Tuberculosis Severity and Treatment Effect: A Directed Screen of 70 Host Markers in a Randomized Clinical Trial

More efficacious treatment regimens are needed for tuberculosis, however, drug development is impeded by a lack of reliable biomarkers of disease severity and of treatment effect. We conducted a directed screen of host biomarkers in participants enrolled in a tuberculosis clinical trial to address t...

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Bibliographic Details
Main Authors: G.B. Sigal, M.R. Segal, A. Mathew, L. Jarlsberg, M. Wang, S. Barbero, N. Small, K. Haynesworth, J.L. Davis, M. Weiner, W.C. Whitworth, J. Jacobs, J. Schorey, D.M. Lewinsohn, P. Nahid
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:EBioMedicine
Subjects:
Host immune response
Tuberculosis
Biomarkers
Clinical trials
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417304176

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