Single-cell profiling reveals molecular basis of malignant phenotypes and tumor microenvironments in small bowel adenocarcinomas

Single-cell profiling reveals molecular basis of malignant phenotypes and tumor microenvironments in small bowel adenocarcinomas

Abstract Small bowel adenocarcinomas (SBAs) are rare malignant tumors with a high mortality rate, and their molecular characteristics are still largely unexplored. Here we performed single-cell RNA sequencing for tumor samples from 12 SBA patients and predicted drug candidates for SBA. We identified...

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Bibliographic Details
Main Authors: Jingwei Yang, Xin Zhou, Ji Dong, Wendong Wang, Yongqu Lu, Yuan Gao, Yu Zhang, Yunuo Mao, Junpeng Gao, Wei Wang, Qingqing Li, Shuai Gao, Lu Wen, Wei Fu, Fuchou Tang
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00434-x

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