Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications
In cardiooncology practice, "early cardiotoxicity" refers to an emerging subclinical myocardial dysfunction/injury in response to certain chemotherapeutic regimens. This condition can progress to overt cardiotoxicity in time and hence warrants proper and timely diagnostic and preventive st...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2023-03-01
|
| Series: | Balkan Medical Journal |
| Online Access: | https://balkanmedicaljournal.org/abstract.php?id=2477 |
| _version_ | 1811155685283463168 |
|---|---|
| author | Kenan Yalta Ertan Yetkin Tülin Yalta |
| author_facet | Kenan Yalta Ertan Yetkin Tülin Yalta |
| author_sort | Kenan Yalta |
| collection | DOAJ |
| description | In cardiooncology practice, "early cardiotoxicity" refers to an emerging subclinical myocardial dysfunction/injury in response to certain chemotherapeutic regimens. This condition can progress to overt cardiotoxicity in time and hence warrants proper and timely diagnostic and preventive strategies. Current diagnostic strategies for "early cardiotoxicity" are largely based on conventional biomarkers and certain echocardiographic indices. However, a significant gap still exists in this setting, warranting further strategies to improve diagnosis and overall prognosis in cancer survivors. Copeptin (surrogate marker of the arginine vasopressine axis) might serve as a promising adjunctive guide for the timely detection, risk stratification, and management of early cardiotoxicity on top of conventional strategies largely due to its multifaceted pathophysiological implications in the clinical setting. This work aims to focus on serum copeptin as a marker of "early cardiotoxicity" and its general clinical implications in patients with cancer. |
| first_indexed | 2024-04-10T04:37:34Z |
| format | Article |
| id | doaj.art-88aa7400019340e6880e6c7e0003b6be |
| institution | Directory Open Access Journal |
| issn | 2146-3123 2146-3131 |
| language | English |
| last_indexed | 2024-04-10T04:37:34Z |
| publishDate | 2023-03-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Balkan Medical Journal |
| spelling | doaj.art-88aa7400019340e6880e6c7e0003b6be2023-03-09T13:47:35ZengGalenos Publishing HouseBalkan Medical Journal2146-31232146-31312023-03-01402829210.4274/balkanmedj.galenos.2023.2023-2-14Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical ImplicationsKenan Yalta0https://orcid.org/0000-0001-5966-2488Ertan Yetkin1https://orcid.org/0000-0001-8862-750XTülin Yalta2https://orcid.org/0000-0002-0699-2739Department of Cardiology, Trakya University Faculty of Medicine, Edirne, TurkeyDepartment of Cardiology, İstinye University Faculty of Medicine, İstanbul, TurkeyDepartment of Pathology, Trakya University Faculty of Medicine, Edirne, TurkeyIn cardiooncology practice, "early cardiotoxicity" refers to an emerging subclinical myocardial dysfunction/injury in response to certain chemotherapeutic regimens. This condition can progress to overt cardiotoxicity in time and hence warrants proper and timely diagnostic and preventive strategies. Current diagnostic strategies for "early cardiotoxicity" are largely based on conventional biomarkers and certain echocardiographic indices. However, a significant gap still exists in this setting, warranting further strategies to improve diagnosis and overall prognosis in cancer survivors. Copeptin (surrogate marker of the arginine vasopressine axis) might serve as a promising adjunctive guide for the timely detection, risk stratification, and management of early cardiotoxicity on top of conventional strategies largely due to its multifaceted pathophysiological implications in the clinical setting. This work aims to focus on serum copeptin as a marker of "early cardiotoxicity" and its general clinical implications in patients with cancer.https://balkanmedicaljournal.org/abstract.php?id=2477 |
| spellingShingle | Kenan Yalta Ertan Yetkin Tülin Yalta Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications Balkan Medical Journal |
| title | Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications |
| title_full | Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications |
| title_fullStr | Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications |
| title_full_unstemmed | Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications |
| title_short | Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications |
| title_sort | serum copeptin in cardiooncology practice review of pathophysiological and clinical implications |
| url | https://balkanmedicaljournal.org/abstract.php?id=2477 |
| work_keys_str_mv | AT kenanyalta serumcopeptinincardiooncologypracticereviewofpathophysiologicalandclinicalimplications AT ertanyetkin serumcopeptinincardiooncologypracticereviewofpathophysiologicalandclinicalimplications AT tulinyalta serumcopeptinincardiooncologypracticereviewofpathophysiologicalandclinicalimplications |