The Role of Immune Modulation in Pathogenesis of IgA Nephropathy

The Role of Immune Modulation in Pathogenesis of IgA Nephropathy

IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis worldwide, with diverse clinical manifestations characterized by recurrent gross hematuria or microscopic hematuria, and pathological changes featuring poorly O-galactosylated IgA1 deposition in the glomerular mesangium. Pathoge...

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Bibliographic Details
Main Authors:	Sheng Chang, Xiao-Kang Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-03-01
Series:	Frontiers in Medicine
Subjects:	glomerular mesangium IgA nephropathy immunopathogenesis mucosal immune innate immunity adaptive immunity
Online Access:	https://www.frontiersin.org/article/10.3389/fmed.2020.00092/full

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