P591: PRELIMINARY RESULTS OF A PHASE I STUDY OF CLIFUTINIB, A HIGHLY SELECTIVE, POTENT ORAL FLT-3 INHIBITOR, IN PATINETS WITH FLT3-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA

Bibliographic Details
Main Authors: W. Yu, X. Wei, Z. Ge, Y. Li, Z. Jiang, L. Yang, L. Lin, Y. Yao, X. Deng, X. Du, T. Chen, X. Feng, J. Zhou, M. Hou, R. Fu, J. Lan, X. Hu, S. Huang, J. Wang, H. Yang, H. Wang, L. Zheng, Z. Wang, B. Liu, N. Kang, Y. Zhuang, Y. Zhang, J. Jin
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/01.HS9.0000845252.68424.50
_version_ 1797287912447934464
author W. Yu
X. Wei
Z. Ge
Y. Li
Z. Jiang
L. Yang
L. Lin
Y. Yao
X. Deng
X. Du
Y. Li
T. Chen
X. Feng
J. Zhou
M. Hou
R. Fu
J. Lan
X. Hu
S. Huang
J. Wang
X. Du
H. Yang
H. Yang
H. Wang
L. Zheng
Z. Wang
B. Liu
N. Kang
Y. Zhuang
Y. Zhang
J. Jin
author_facet W. Yu
X. Wei
Z. Ge
Y. Li
Z. Jiang
L. Yang
L. Lin
Y. Yao
X. Deng
X. Du
Y. Li
T. Chen
X. Feng
J. Zhou
M. Hou
R. Fu
J. Lan
X. Hu
S. Huang
J. Wang
X. Du
H. Yang
H. Yang
H. Wang
L. Zheng
Z. Wang
B. Liu
N. Kang
Y. Zhuang
Y. Zhang
J. Jin
author_sort W. Yu
collection DOAJ
first_indexed 2024-03-07T18:41:42Z
format Article
id doaj.art-88ae46856040486896cb51bcdeb03ffc
institution Directory Open Access Journal
issn 2572-9241
language English
last_indexed 2024-03-07T18:41:42Z
publishDate 2022-06-01
publisher Wiley
record_format Article
series HemaSphere
spelling doaj.art-88ae46856040486896cb51bcdeb03ffc2024-03-02T03:51:51ZengWileyHemaSphere2572-92412022-06-01649049110.1097/01.HS9.0000845252.68424.50202206003-00490P591: PRELIMINARY RESULTS OF A PHASE I STUDY OF CLIFUTINIB, A HIGHLY SELECTIVE, POTENT ORAL FLT-3 INHIBITOR, IN PATINETS WITH FLT3-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIAW. Yu0X. Wei1Z. Ge2Y. Li3Z. Jiang4L. Yang5L. Lin6Y. Yao7X. Deng8X. Du9Y. Li10T. Chen11X. Feng12J. Zhou13M. Hou14R. Fu15J. Lan16X. Hu17S. Huang18J. Wang19X. Du20H. Yang21H. Yang22H. Wang23L. Zheng24Z. Wang25B. Liu26N. Kang27Y. Zhuang28Y. Zhang29J. Jin301 The First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou2 Henan Cancer Hospital, Zhengzhou3 Zhongda Hospital, Southeast University, Nanjing4 Zhujiang Hospital of Southern Medical University, Guangzhou5 The First Affiliated Hospital of Zhengzhou University, Zhengzhou6 The Second Hospital of Shanxi Medical University, Taiyuan7 ​Hainan General Hospital, Haikou8 Baoji Central Hospital, Baoji9 Weihai Municipal Hospital, Weihai10 Guangdong General Hospital11 Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou12 Huashan Hospital, Shanghai13 The Affiliated Hospital of Qingdao University, Qingdao14 Wuhan Tongji Hospital, Wuhan15 Qilu Hospital of Shandong University, Jinan16 Tianjin Medical University General Hospital, Tianjin17 Zhejiang Provincial People’s Hospital, Hangzhou18 Beida Medical Treatment Luzhong Hospital, Zibo19 Xi’an Gaoxin Hospital, Xian20 Aerospace Center Hospital, Beijing21 The Second People’s Hospital of Shenzhen, Shenzhen22 Shunde Hospital of Southern Medical University, Foshan23 The 1st Affiliated Hospital of He’nan University of Science and Technology, Luoyang1 The First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou24 Sunshine Lake Pharma Co., Ltd, Dongguan, China24 Sunshine Lake Pharma Co., Ltd, Dongguan, China24 Sunshine Lake Pharma Co., Ltd, Dongguan, China24 Sunshine Lake Pharma Co., Ltd, Dongguan, China24 Sunshine Lake Pharma Co., Ltd, Dongguan, China24 Sunshine Lake Pharma Co., Ltd, Dongguan, China1 The First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhouhttp://journals.lww.com/10.1097/01.HS9.0000845252.68424.50
spellingShingle W. Yu
X. Wei
Z. Ge
Y. Li
Z. Jiang
L. Yang
L. Lin
Y. Yao
X. Deng
X. Du
Y. Li
T. Chen
X. Feng
J. Zhou
M. Hou
R. Fu
J. Lan
X. Hu
S. Huang
J. Wang
X. Du
H. Yang
H. Yang
H. Wang
L. Zheng
Z. Wang
B. Liu
N. Kang
Y. Zhuang
Y. Zhang
J. Jin
P591: PRELIMINARY RESULTS OF A PHASE I STUDY OF CLIFUTINIB, A HIGHLY SELECTIVE, POTENT ORAL FLT-3 INHIBITOR, IN PATINETS WITH FLT3-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA
HemaSphere
title P591: PRELIMINARY RESULTS OF A PHASE I STUDY OF CLIFUTINIB, A HIGHLY SELECTIVE, POTENT ORAL FLT-3 INHIBITOR, IN PATINETS WITH FLT3-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA
title_full P591: PRELIMINARY RESULTS OF A PHASE I STUDY OF CLIFUTINIB, A HIGHLY SELECTIVE, POTENT ORAL FLT-3 INHIBITOR, IN PATINETS WITH FLT3-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA
title_fullStr P591: PRELIMINARY RESULTS OF A PHASE I STUDY OF CLIFUTINIB, A HIGHLY SELECTIVE, POTENT ORAL FLT-3 INHIBITOR, IN PATINETS WITH FLT3-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA
title_full_unstemmed P591: PRELIMINARY RESULTS OF A PHASE I STUDY OF CLIFUTINIB, A HIGHLY SELECTIVE, POTENT ORAL FLT-3 INHIBITOR, IN PATINETS WITH FLT3-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA
title_short P591: PRELIMINARY RESULTS OF A PHASE I STUDY OF CLIFUTINIB, A HIGHLY SELECTIVE, POTENT ORAL FLT-3 INHIBITOR, IN PATINETS WITH FLT3-MUTATED RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA
title_sort p591 preliminary results of a phase i study of clifutinib a highly selective potent oral flt 3 inhibitor in patinets with flt3 mutated relapsed or refractory acute myeloid leukemia
url http://journals.lww.com/10.1097/01.HS9.0000845252.68424.50
work_keys_str_mv AT wyu p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT xwei p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT zge p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT yli p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT zjiang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT lyang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT llin p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT yyao p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT xdeng p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT xdu p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT yli p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT tchen p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT xfeng p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT jzhou p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT mhou p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT rfu p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT jlan p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT xhu p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT shuang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT jwang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT xdu p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT hyang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT hyang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT hwang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT lzheng p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT zwang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT bliu p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT nkang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT yzhuang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT yzhang p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia
AT jjin p591preliminaryresultsofaphaseistudyofclifutinibahighlyselectivepotentoralflt3inhibitorinpatinetswithflt3mutatedrelapsedorrefractoryacutemyeloidleukemia