| Summary: | The study of the enzyme activity in 5 cases of normal vitreous humour, subretinal fluid and sera in 52 cases of rhegmatogenous retinal detachment lead to the following conclusions : 1) The activity of amylase in subretinal fluid tends to rise with the increase in the duration of retinal detachment There is significant difference in the amylase activity upto 24 weeks of duration, of retinal detachment 2) There is no significant change in the mean value of GOT level in SRF with the increase in the duration of retinal detachment 3) The mean GPT level of SRF decreases with the increase in the duration of retinal detachment There is a significant difference between the mean values of GPT upto 6 weeks 4) The lower value of amylase in subretinal fluid is associated with good prognosis 5) The activity of GOT in SRF has got no significant relation to the outcome of surgery. 6) The higher value of GPT in SRF is associated with good surgical results and lower value with poor result 7) There is no significant change in the concentration of amylase, GOT and GPT activity in serum in relation to the duration of retinal detachment 8) There is also no significant correlation between the level of amylase, GOT and GPT in blood depending on the result of surgery. 9) Both vitreous and blood appear to contribute to the origin of subretinal fluid.
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