To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in Plants
Gene expression in eukaryotes is controlled at multiple levels, including transcriptional and post-transcriptional levels. The transcriptional regulation of gene expression is complex and includes the regulation of the initiation and elongation phases of transcription. Meanwhile, the post-transcript...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-10-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fpls.2019.01222/full |
| _version_ | 1818511043965485056 |
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| author | Ying Cao Ligeng Ma |
| author_facet | Ying Cao Ligeng Ma |
| author_sort | Ying Cao |
| collection | DOAJ |
| description | Gene expression in eukaryotes is controlled at multiple levels, including transcriptional and post-transcriptional levels. The transcriptional regulation of gene expression is complex and includes the regulation of the initiation and elongation phases of transcription. Meanwhile, the post-transcriptional regulation of gene expression includes precursor messenger RNA (pre-mRNA) splicing, 5′ capping, and 3′ polyadenylation. Among these events, pre-mRNA splicing, conducted by the spliceosome, plays a key role in the regulation of gene expression, and the efficiency and precision of pre-mRNA splicing are critical for gene function. Ski-interacting protein (SKIP) is an evolutionarily conserved protein from yeast to humans. In plants, SKIP is a bifunctional regulator that works as a splicing factor as part of the spliceosome and as a transcriptional regulator via interactions with the transcriptional regulatory complex. Here, we review how the functions of SKIP as a splicing factor and a transcriptional regulator affect environmental fitness and development in plants. |
| first_indexed | 2024-12-10T23:28:10Z |
| format | Article |
| id | doaj.art-88b89587bda5470982b5cb30e0bee8aa |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-10T23:28:10Z |
| publishDate | 2019-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-88b89587bda5470982b5cb30e0bee8aa2022-12-22T01:29:31ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2019-10-011010.3389/fpls.2019.01222479055To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in PlantsYing CaoLigeng MaGene expression in eukaryotes is controlled at multiple levels, including transcriptional and post-transcriptional levels. The transcriptional regulation of gene expression is complex and includes the regulation of the initiation and elongation phases of transcription. Meanwhile, the post-transcriptional regulation of gene expression includes precursor messenger RNA (pre-mRNA) splicing, 5′ capping, and 3′ polyadenylation. Among these events, pre-mRNA splicing, conducted by the spliceosome, plays a key role in the regulation of gene expression, and the efficiency and precision of pre-mRNA splicing are critical for gene function. Ski-interacting protein (SKIP) is an evolutionarily conserved protein from yeast to humans. In plants, SKIP is a bifunctional regulator that works as a splicing factor as part of the spliceosome and as a transcriptional regulator via interactions with the transcriptional regulatory complex. Here, we review how the functions of SKIP as a splicing factor and a transcriptional regulator affect environmental fitness and development in plants.https://www.frontiersin.org/article/10.3389/fpls.2019.01222/fullSKIPalternative splicingtranscriptional regulatorsplicing factorenvironmental fitnessplant development |
| spellingShingle | Ying Cao Ligeng Ma To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in Plants Frontiers in Plant Science SKIP alternative splicing transcriptional regulator splicing factor environmental fitness plant development |
| title | To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in Plants |
| title_full | To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in Plants |
| title_fullStr | To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in Plants |
| title_full_unstemmed | To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in Plants |
| title_short | To Splice or to Transcribe: SKIP-Mediated Environmental Fitness and Development in Plants |
| title_sort | to splice or to transcribe skip mediated environmental fitness and development in plants |
| topic | SKIP alternative splicing transcriptional regulator splicing factor environmental fitness plant development |
| url | https://www.frontiersin.org/article/10.3389/fpls.2019.01222/full |
| work_keys_str_mv | AT yingcao tospliceortotranscribeskipmediatedenvironmentalfitnessanddevelopmentinplants AT ligengma tospliceortotranscribeskipmediatedenvironmentalfitnessanddevelopmentinplants |