Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma
Platelet rich plasma (PRP) is an autologous biological product harvested by consecutive centrifugations of whole blood and separation of plasma in a stepwise protocol. PRP has been successfully used to stimulate healing in orthopedic and dermatological conditions, both in humans and animals. The pri...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2018-12-01
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| Series: | Acta Veterinaria |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/acve-2018-0038 |
| _version_ | 1798033115908669440 |
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| author | Miranda Stephania De Mello Costa Maria Fernanda Jeunon Senna Juliana Frapoint João Castañon De Alencar Nayro Xavier Barroso Lessa Daniel Augusto |
| author_facet | Miranda Stephania De Mello Costa Maria Fernanda Jeunon Senna Juliana Frapoint João Castañon De Alencar Nayro Xavier Barroso Lessa Daniel Augusto |
| author_sort | Miranda Stephania |
| collection | DOAJ |
| description | Platelet rich plasma (PRP) is an autologous biological product harvested by consecutive centrifugations of whole blood and separation of plasma in a stepwise protocol. PRP has been successfully used to stimulate healing in orthopedic and dermatological conditions, both in humans and animals. The principle is the fact that α- granules inside platelets contain a high concentration of growth factors, that once released can interfere with cellular communication and speed up healing. Standardization of PRP requires establishing a gold standard for the preparation and evaluation of the product, especially considering that platelet concentration and, therefore, growth factor concentration, might vary due to a number of variables. Factors such as age, gender, race or breed, and immune status of the patient might interfere with PRP quality and with treatment results, although little is known about such interferences. This research investigated the effect of breed/species and gender in platelet concentration in autologous PRP from horses and mules. The results demonstrate that Quarter Horses provided PRP with the greatest amount of platelets, although mules had a higher concentration percentages in relation to the initial platelet counts. |
| first_indexed | 2024-04-11T20:24:58Z |
| format | Article |
| id | doaj.art-88ba0f82c06c4c2395f1c3cddabaed57 |
| institution | Directory Open Access Journal |
| issn | 1820-7448 |
| language | English |
| last_indexed | 2024-04-11T20:24:58Z |
| publishDate | 2018-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Veterinaria |
| spelling | doaj.art-88ba0f82c06c4c2395f1c3cddabaed572022-12-22T04:04:41ZengSciendoActa Veterinaria1820-74482018-12-0168447448310.2478/acve-2018-0038Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich PlasmaMiranda Stephania0De Mello Costa Maria Fernanda1Jeunon Senna Juliana2Frapoint João Castañon3De Alencar Nayro Xavier4Barroso Lessa Daniel Augusto5Departamento de Patologia e Clínica Veterinária, Faculdade de Veterinária, Niterói, Brazil;CHASP, Waikato Institute of Technology, Hamilton, New Zealand;Curso de Medicina Veterinária, Faculdade de Veterinária, Niterói, BrazilCurso de Medicina Veterinária, Faculdade de Veterinária, Niterói, BrazilDepartamento de Patologia e Clínica Veterinária, Faculdade de Veterinária, Niterói, Brazil;Departamento de Patologia e Clínica Veterinária, Faculdade de Veterinária, Niterói, Brazil;Platelet rich plasma (PRP) is an autologous biological product harvested by consecutive centrifugations of whole blood and separation of plasma in a stepwise protocol. PRP has been successfully used to stimulate healing in orthopedic and dermatological conditions, both in humans and animals. The principle is the fact that α- granules inside platelets contain a high concentration of growth factors, that once released can interfere with cellular communication and speed up healing. Standardization of PRP requires establishing a gold standard for the preparation and evaluation of the product, especially considering that platelet concentration and, therefore, growth factor concentration, might vary due to a number of variables. Factors such as age, gender, race or breed, and immune status of the patient might interfere with PRP quality and with treatment results, although little is known about such interferences. This research investigated the effect of breed/species and gender in platelet concentration in autologous PRP from horses and mules. The results demonstrate that Quarter Horses provided PRP with the greatest amount of platelets, although mules had a higher concentration percentages in relation to the initial platelet counts.https://doi.org/10.2478/acve-2018-0038biological productsblood plateletshorsesmethods |
| spellingShingle | Miranda Stephania De Mello Costa Maria Fernanda Jeunon Senna Juliana Frapoint João Castañon De Alencar Nayro Xavier Barroso Lessa Daniel Augusto Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma Acta Veterinaria biological products blood platelets horses methods |
| title | Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma |
| title_full | Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma |
| title_fullStr | Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma |
| title_full_unstemmed | Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma |
| title_short | Effects of Breed/Species and Gender on Platelet Concentration in Autologous Platelet Rich Plasma |
| title_sort | effects of breed species and gender on platelet concentration in autologous platelet rich plasma |
| topic | biological products blood platelets horses methods |
| url | https://doi.org/10.2478/acve-2018-0038 |
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