Antibacterial potential of a mouthwash based on Azadirachta indica (neem) on oral pathogens
Introduction: The high prevalence of oral diseases and the side effects of synthetic drugs has promoted the study of therapeutic alternatives such as medicinal plants that are safe, effective and economical for the population. Objective: To evaluate the antibacterial potential of 2 mouthwashes based...
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| Format: | Article |
| Language: | Spanish |
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ECIMED
2023-05-01
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| Series: | Revista Cubana de Medicina Militar |
| Subjects: | |
| Online Access: | https://revmedmilitar.sld.cu/index.php/mil/article/view/2386 |
| _version_ | 1797802319592554496 |
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| author | Miguel Angel Ruiz-Barrueto Wilfredo Terrones-Campos Daniela Alejandra Cueva-Yesán María Félix Sánchez-Villavicencio José Elías Cabrejo-Paredes |
| author_facet | Miguel Angel Ruiz-Barrueto Wilfredo Terrones-Campos Daniela Alejandra Cueva-Yesán María Félix Sánchez-Villavicencio José Elías Cabrejo-Paredes |
| author_sort | Miguel Angel Ruiz-Barrueto |
| collection | DOAJ |
| description | Introduction: The high prevalence of oral diseases and the side effects of synthetic drugs has promoted the study of therapeutic alternatives such as medicinal plants that are safe, effective and economical for the population.
Objective: To evaluate the antibacterial potential of 2 mouthwashes based on Azadirachta indica (neem) on Streptococcus mutans and Enterococcus faecalis.
Methods: Experimental study. Two mouthwashes were made from the hydroethanolic extract of neen with concentrations of 25 mg/mL and 50 mg/mL. The antibacterial potential was evaluated by the disk diffusion method. The data were analyzed with ANOVA and Tukey in the statistical package SPSS v.26.
Results: For Streptococcus mutans, the halo of the mouthwash with 25 mg/mL of neem extract was 25.12 ± 0.798 mm; that of 50 mg/mL formed a halo of 29.40 ± 1.197 mm; the negative control a halo of 8.62 ± 0.132 mm and chlorhexidine 0.12% a halo of 17.64 ± 0.160 mm. For Enterococcus faecalis , the halo of the mouthwash with 25 mg/mL was 18.23 ± 1,150 mm; that of 50 mg/mL a halo of 20.93 ± 0.487 mm; the negative control a halo of 7.91 ± 0.417 mm and chlorhexidine 0.12% a halo of 16.50 ± 0.505 mm.
Conclusion: Neem-based mouthwashes have in vitro antibacterial potential against Streptococcus mutans and Enterococcus faecalis and could be used in the future to control them and other oral pathogens. |
| first_indexed | 2024-03-13T05:03:54Z |
| format | Article |
| id | doaj.art-88bb3e48a7474d0eb47e71857480f603 |
| institution | Directory Open Access Journal |
| issn | 1561-3046 |
| language | Spanish |
| last_indexed | 2024-03-13T05:03:54Z |
| publishDate | 2023-05-01 |
| publisher | ECIMED |
| record_format | Article |
| series | Revista Cubana de Medicina Militar |
| spelling | doaj.art-88bb3e48a7474d0eb47e71857480f6032023-06-17T04:25:56ZspaECIMEDRevista Cubana de Medicina Militar1561-30462023-05-01522e02302386e02302386775Antibacterial potential of a mouthwash based on Azadirachta indica (neem) on oral pathogensMiguel Angel Ruiz-Barrueto0Wilfredo Terrones-Campos1Daniela Alejandra Cueva-Yesán2María Félix Sánchez-Villavicencio3José Elías Cabrejo-Paredes4Universidad César VallejoUniversidad Nacional de PiuraCentro de Salud La CruzUniversidad Nacional Agraria de La SelvaUniversidad Nacional de TrujilloIntroduction: The high prevalence of oral diseases and the side effects of synthetic drugs has promoted the study of therapeutic alternatives such as medicinal plants that are safe, effective and economical for the population. Objective: To evaluate the antibacterial potential of 2 mouthwashes based on Azadirachta indica (neem) on Streptococcus mutans and Enterococcus faecalis. Methods: Experimental study. Two mouthwashes were made from the hydroethanolic extract of neen with concentrations of 25 mg/mL and 50 mg/mL. The antibacterial potential was evaluated by the disk diffusion method. The data were analyzed with ANOVA and Tukey in the statistical package SPSS v.26. Results: For Streptococcus mutans, the halo of the mouthwash with 25 mg/mL of neem extract was 25.12 ± 0.798 mm; that of 50 mg/mL formed a halo of 29.40 ± 1.197 mm; the negative control a halo of 8.62 ± 0.132 mm and chlorhexidine 0.12% a halo of 17.64 ± 0.160 mm. For Enterococcus faecalis , the halo of the mouthwash with 25 mg/mL was 18.23 ± 1,150 mm; that of 50 mg/mL a halo of 20.93 ± 0.487 mm; the negative control a halo of 7.91 ± 0.417 mm and chlorhexidine 0.12% a halo of 16.50 ± 0.505 mm. Conclusion: Neem-based mouthwashes have in vitro antibacterial potential against Streptococcus mutans and Enterococcus faecalis and could be used in the future to control them and other oral pathogens.https://revmedmilitar.sld.cu/index.php/mil/article/view/2386antibacterianosextractos vegetalesazadirachtastreptococcus mutansenterococcus faecalisantisépticos bucales. |
| spellingShingle | Miguel Angel Ruiz-Barrueto Wilfredo Terrones-Campos Daniela Alejandra Cueva-Yesán María Félix Sánchez-Villavicencio José Elías Cabrejo-Paredes Antibacterial potential of a mouthwash based on Azadirachta indica (neem) on oral pathogens Revista Cubana de Medicina Militar antibacterianos extractos vegetales azadirachta streptococcus mutans enterococcus faecalis antisépticos bucales. |
| title | Antibacterial potential of a mouthwash based on Azadirachta indica (neem) on oral pathogens |
| title_full | Antibacterial potential of a mouthwash based on Azadirachta indica (neem) on oral pathogens |
| title_fullStr | Antibacterial potential of a mouthwash based on Azadirachta indica (neem) on oral pathogens |
| title_full_unstemmed | Antibacterial potential of a mouthwash based on Azadirachta indica (neem) on oral pathogens |
| title_short | Antibacterial potential of a mouthwash based on Azadirachta indica (neem) on oral pathogens |
| title_sort | antibacterial potential of a mouthwash based on azadirachta indica neem on oral pathogens |
| topic | antibacterianos extractos vegetales azadirachta streptococcus mutans enterococcus faecalis antisépticos bucales. |
| url | https://revmedmilitar.sld.cu/index.php/mil/article/view/2386 |
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