Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia
Computed tomography (CT) has been an essential diagnostic tool during the COVID-19 pandemic. The study aimed to develop an optimal CT protocol in terms of safety and reliability. For this, we assessed the inter-observer agreement between CT and low-dose CT (LDCT) with soft and sharp kernels using a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/3/669 |
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| author | Ivan Blokhin Victor Gombolevskiy Valeria Chernina Maxim Gusev Pavel Gelezhe Olga Aleshina Alexander Nikolaev Nicholas Kulberg Sergey Morozov Roman Reshetnikov |
| author_facet | Ivan Blokhin Victor Gombolevskiy Valeria Chernina Maxim Gusev Pavel Gelezhe Olga Aleshina Alexander Nikolaev Nicholas Kulberg Sergey Morozov Roman Reshetnikov |
| author_sort | Ivan Blokhin |
| collection | DOAJ |
| description | Computed tomography (CT) has been an essential diagnostic tool during the COVID-19 pandemic. The study aimed to develop an optimal CT protocol in terms of safety and reliability. For this, we assessed the inter-observer agreement between CT and low-dose CT (LDCT) with soft and sharp kernels using a semi-quantitative severity scale in a prospective study (Moscow, Russia). Two consecutive scans with CT and LDCT were performed in a single visit. Reading was performed by ten radiologists with 3–25 years’ experience. The study included 230 patients, and statistical analysis showed LDCT with a sharp kernel as the most reliable protocol (percentage agreement 74.35 ± 43.77%), but its advantage was marginal. There was no significant correlation between radiologists’ experience and average percentage agreement for all four evaluated protocols. Regarding the radiation exposure, CTDI<sub>vol</sub> was 3.6 ± 0.64 times lower for LDCT. In conclusion, CT and LDCT with soft and sharp reconstructions are equally reliable for COVID-19 reporting using the “CT 0-4” scale. The LDCT protocol allows for a significant decrease in radiation exposure but may be restricted by body mass index. |
| first_indexed | 2024-03-09T23:41:01Z |
| format | Article |
| id | doaj.art-88bf5bd6af234d4da108ed1e2ce3bc36 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T23:41:01Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-88bf5bd6af234d4da108ed1e2ce3bc362023-11-23T16:52:10ZengMDPI AGJournal of Clinical Medicine2077-03832022-01-0111366910.3390/jcm11030669Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 PneumoniaIvan Blokhin0Victor Gombolevskiy1Valeria Chernina2Maxim Gusev3Pavel Gelezhe4Olga Aleshina5Alexander Nikolaev6Nicholas Kulberg7Sergey Morozov8Roman Reshetnikov9Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, 127051 Moscow, RussiaArtificial Intelligence Research Institute (AIRI), 105064 Moscow, RussiaResearch and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, 127051 Moscow, RussiaMoscow Polytechnic University, 107023 Moscow, RussiaResearch and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, 127051 Moscow, RussiaCity Clinical Hospital No. 13 of the Moscow Health Care Department, 115280 Moscow, RussiaResearch and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, 127051 Moscow, RussiaFederal Research Center “Computer Science and Control” of Russian Academy of Sciences, 119333 Moscow, RussiaResearch and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, 127051 Moscow, RussiaResearch and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, 127051 Moscow, RussiaComputed tomography (CT) has been an essential diagnostic tool during the COVID-19 pandemic. The study aimed to develop an optimal CT protocol in terms of safety and reliability. For this, we assessed the inter-observer agreement between CT and low-dose CT (LDCT) with soft and sharp kernels using a semi-quantitative severity scale in a prospective study (Moscow, Russia). Two consecutive scans with CT and LDCT were performed in a single visit. Reading was performed by ten radiologists with 3–25 years’ experience. The study included 230 patients, and statistical analysis showed LDCT with a sharp kernel as the most reliable protocol (percentage agreement 74.35 ± 43.77%), but its advantage was marginal. There was no significant correlation between radiologists’ experience and average percentage agreement for all four evaluated protocols. Regarding the radiation exposure, CTDI<sub>vol</sub> was 3.6 ± 0.64 times lower for LDCT. In conclusion, CT and LDCT with soft and sharp reconstructions are equally reliable for COVID-19 reporting using the “CT 0-4” scale. The LDCT protocol allows for a significant decrease in radiation exposure but may be restricted by body mass index.https://www.mdpi.com/2077-0383/11/3/669COVID-19SARS-CoV-2pneumoniatomographyX-ray computed |
| spellingShingle | Ivan Blokhin Victor Gombolevskiy Valeria Chernina Maxim Gusev Pavel Gelezhe Olga Aleshina Alexander Nikolaev Nicholas Kulberg Sergey Morozov Roman Reshetnikov Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia Journal of Clinical Medicine COVID-19 SARS-CoV-2 pneumonia tomography X-ray computed |
| title | Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia |
| title_full | Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia |
| title_fullStr | Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia |
| title_full_unstemmed | Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia |
| title_short | Inter-Observer Agreement between Low-Dose and Standard-Dose CT with Soft and Sharp Convolution Kernels in COVID-19 Pneumonia |
| title_sort | inter observer agreement between low dose and standard dose ct with soft and sharp convolution kernels in covid 19 pneumonia |
| topic | COVID-19 SARS-CoV-2 pneumonia tomography X-ray computed |
| url | https://www.mdpi.com/2077-0383/11/3/669 |
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