How Phosphofructokinase-1 Promotes PI3K and YAP/TAZ in Cancer: Therapeutic Perspectives

How Phosphofructokinase-1 Promotes PI3K and YAP/TAZ in Cancer: Therapeutic Perspectives

PI3K/AKT is one of the most frequently altered signaling pathways in human cancers, supporting the activation of many proteins sustaining cell metabolism, proliferation, and aggressiveness. Another important pathway frequently altered in cancer cells is the one regulating the YAP/TAZ transcriptional...

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Bibliographic Details
Main Authors: Luca Simula, Marco Alifano, Philippe Icard
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cancers
Subjects:
PFK1
F-1,6-BP
PI3K
YAP/TAZ
drug resistance
citrate
Online Access:https://www.mdpi.com/2072-6694/14/10/2478

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