Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors
Several cancer risk factors (exposure to ultraviolet-B, pollution, toxins and pathogens) have been identified for wildlife, to form a “cancer risk landscape.” However, information remains limited on how the spatiotemporal variability of these factors impacts the prevalence of cancer in wildlife. Her...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/10/10/1295 |
| _version_ | 1797513491603521536 |
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| author | Antoine M. Dujon Gail Schofield Roberto M. Venegas Frédéric Thomas Beata Ujvari |
| author_facet | Antoine M. Dujon Gail Schofield Roberto M. Venegas Frédéric Thomas Beata Ujvari |
| author_sort | Antoine M. Dujon |
| collection | DOAJ |
| description | Several cancer risk factors (exposure to ultraviolet-B, pollution, toxins and pathogens) have been identified for wildlife, to form a “cancer risk landscape.” However, information remains limited on how the spatiotemporal variability of these factors impacts the prevalence of cancer in wildlife. Here, we evaluated the cancer risk landscape at 49 foraging sites of the globally distributed green turtle (<i>Chelonia mydas</i>), a species affected by fibropapillomatosis, by integrating data from a global meta-analysis of 31 publications (1994–2019). Evaluated risk factors included ultraviolet light exposure, eutrophication, toxic phytoplanktonic blooms, sea surface temperature, and the presence of mechanical vectors (parasites and symbiotic species). Prevalence was highest in areas where nutrient concentrations facilitated the emergence of toxic phytoplankton blooms. In contrast, ultraviolet light exposure and the presence of parasitic and/or symbiotic species did not appear to impact disease prevalence. Our results indicate that, to counter outbreaks of fibropapillomatosis, management actions that reduce eutrophication in foraging areas should be implemented. |
| first_indexed | 2024-03-10T06:17:20Z |
| format | Article |
| id | doaj.art-88c7b2ec08b84ec09b11dfd35b33a435 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T06:17:20Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-88c7b2ec08b84ec09b11dfd35b33a4352023-11-22T19:33:49ZengMDPI AGPathogens2076-08172021-10-011010129510.3390/pathogens10101295Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk FactorsAntoine M. Dujon0Gail Schofield1Roberto M. Venegas2Frédéric Thomas3Beata Ujvari4Centre for Integrative Ecology, School of Life and Environmental Sciences, Deakin University, Geelong Waurn Ponds, Vic 3216, AustraliaSchool of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UKCentre for Integrative Ecology, School of Life and Environmental Sciences, Deakin University, Geelong Waurn Ponds, Vic 3216, AustraliaCANECEV-Centre de Recherches Ecologiques et Evolutives sur le Cancer (CREEC), 34090 Montpellier, FranceCentre for Integrative Ecology, School of Life and Environmental Sciences, Deakin University, Geelong Waurn Ponds, Vic 3216, AustraliaSeveral cancer risk factors (exposure to ultraviolet-B, pollution, toxins and pathogens) have been identified for wildlife, to form a “cancer risk landscape.” However, information remains limited on how the spatiotemporal variability of these factors impacts the prevalence of cancer in wildlife. Here, we evaluated the cancer risk landscape at 49 foraging sites of the globally distributed green turtle (<i>Chelonia mydas</i>), a species affected by fibropapillomatosis, by integrating data from a global meta-analysis of 31 publications (1994–2019). Evaluated risk factors included ultraviolet light exposure, eutrophication, toxic phytoplanktonic blooms, sea surface temperature, and the presence of mechanical vectors (parasites and symbiotic species). Prevalence was highest in areas where nutrient concentrations facilitated the emergence of toxic phytoplankton blooms. In contrast, ultraviolet light exposure and the presence of parasitic and/or symbiotic species did not appear to impact disease prevalence. Our results indicate that, to counter outbreaks of fibropapillomatosis, management actions that reduce eutrophication in foraging areas should be implemented.https://www.mdpi.com/2076-0817/10/10/1295epidemiologyneoplasmlandscape ecologyconservationcumulative impactclimate change |
| spellingShingle | Antoine M. Dujon Gail Schofield Roberto M. Venegas Frédéric Thomas Beata Ujvari Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors Pathogens epidemiology neoplasm landscape ecology conservation cumulative impact climate change |
| title | Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors |
| title_full | Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors |
| title_fullStr | Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors |
| title_full_unstemmed | Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors |
| title_short | Sea Turtles in the Cancer Risk Landscape: A Global Meta-Analysis of Fibropapillomatosis Prevalence and Associated Risk Factors |
| title_sort | sea turtles in the cancer risk landscape a global meta analysis of fibropapillomatosis prevalence and associated risk factors |
| topic | epidemiology neoplasm landscape ecology conservation cumulative impact climate change |
| url | https://www.mdpi.com/2076-0817/10/10/1295 |
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