Reversible cerebral and brain stem dysfunction in n: Hexane neuropathy
A 18-year-old male, screen printer by profession developed sensory motor polyneuropathy, change in his behavior, bilateral 6 th and 7 th cranial nerve palsies, down beat nystagmus and cerebellar dysarthria. He had bilaterally prolonged P100 latency; left: 137 ms; right: 144 ms. P 37 was not recordab...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Annals of Indian Academy of Neurology |
| Subjects: | |
| Online Access: | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=4;spage=464;epage=467;aulast=Puri |
| _version_ | 1818130257874518016 |
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| author | Vinod Puri Abhijit Das Gupta Neera Chaudhry Ravindra Kumar Saran |
| author_facet | Vinod Puri Abhijit Das Gupta Neera Chaudhry Ravindra Kumar Saran |
| author_sort | Vinod Puri |
| collection | DOAJ |
| description | A 18-year-old male, screen printer by profession developed sensory motor polyneuropathy, change in his behavior, bilateral 6 th and 7 th cranial nerve palsies, down beat nystagmus and cerebellar dysarthria. He had bilaterally prolonged P100 latency; left: 137 ms; right: 144 ms. P 37 was not recordable on either side while N 20 was normal. The inter latency difference between Ipsilateral R2 and Contralateral R2 was 6.15 ms, on the left side and normal on the right side. In the follow-up, there was normalization of the blink reflex study, improvement in P100 latency [left: 114 ms; right: 120 ms.] but worsening of peripheral nerve conductions. The sequential clinical recovery was of the behavioral dysfunction, down beat nystagmus, 6 th nerve, 7 th nerve involvement and ataxia, in that order. Sural nerve biopsy showed loss of large diameter myelinated fibers. |
| first_indexed | 2024-12-11T08:02:10Z |
| format | Article |
| id | doaj.art-88c91d2eb3ba47c1a52151722f6aaa1e |
| institution | Directory Open Access Journal |
| issn | 0972-2327 1998-3549 |
| language | English |
| last_indexed | 2024-12-11T08:02:10Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj.art-88c91d2eb3ba47c1a52151722f6aaa1e2022-12-22T01:15:06ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492015-01-0118446446710.4103/0972-2327.160088Reversible cerebral and brain stem dysfunction in n: Hexane neuropathyVinod PuriAbhijit Das GuptaNeera ChaudhryRavindra Kumar SaranA 18-year-old male, screen printer by profession developed sensory motor polyneuropathy, change in his behavior, bilateral 6 th and 7 th cranial nerve palsies, down beat nystagmus and cerebellar dysarthria. He had bilaterally prolonged P100 latency; left: 137 ms; right: 144 ms. P 37 was not recordable on either side while N 20 was normal. The inter latency difference between Ipsilateral R2 and Contralateral R2 was 6.15 ms, on the left side and normal on the right side. In the follow-up, there was normalization of the blink reflex study, improvement in P100 latency [left: 114 ms; right: 120 ms.] but worsening of peripheral nerve conductions. The sequential clinical recovery was of the behavioral dysfunction, down beat nystagmus, 6 th nerve, 7 th nerve involvement and ataxia, in that order. Sural nerve biopsy showed loss of large diameter myelinated fibers.http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=4;spage=464;epage=467;aulast=Puri6 th and 7 th nerve palsyblink reflexcentral nervous system involvementdown beat nystagmusn- Hexane neuropathy |
| spellingShingle | Vinod Puri Abhijit Das Gupta Neera Chaudhry Ravindra Kumar Saran Reversible cerebral and brain stem dysfunction in n: Hexane neuropathy Annals of Indian Academy of Neurology 6 th and 7 th nerve palsy blink reflex central nervous system involvement down beat nystagmus n- Hexane neuropathy |
| title | Reversible cerebral and brain stem dysfunction in n: Hexane neuropathy |
| title_full | Reversible cerebral and brain stem dysfunction in n: Hexane neuropathy |
| title_fullStr | Reversible cerebral and brain stem dysfunction in n: Hexane neuropathy |
| title_full_unstemmed | Reversible cerebral and brain stem dysfunction in n: Hexane neuropathy |
| title_short | Reversible cerebral and brain stem dysfunction in n: Hexane neuropathy |
| title_sort | reversible cerebral and brain stem dysfunction in n hexane neuropathy |
| topic | 6 th and 7 th nerve palsy blink reflex central nervous system involvement down beat nystagmus n- Hexane neuropathy |
| url | http://www.annalsofian.org/article.asp?issn=0972-2327;year=2015;volume=18;issue=4;spage=464;epage=467;aulast=Puri |
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