Central nervous system tumors in patients coming from areas of conflict in the Middle East/North Africa region: an experience from King Hussein Cancer Center
IntroductionThe global cancer burden has been disproportionately shifting towards low- and middle-income countries (LMICs). Limited availability and accessibility to screening, treatment and surveillance, increase in the prevalence and lack of control of risk factors, and underdeveloped healthcare i...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1087987/full |
| _version_ | 1797825187987587072 |
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| author | Mouness Obeidat Jamil Nazzal Sarah Al Sharie Ahmed Mahmoud Al-Azzam Ahmad Maswadeh Haneen Al-Abdallat Layan Ismail Marah Alkderat Ro’ya Hzayen Yasmeen Al-Sheble Asem Mansour Maysa Al-Hussaini |
| author_facet | Mouness Obeidat Jamil Nazzal Sarah Al Sharie Ahmed Mahmoud Al-Azzam Ahmad Maswadeh Haneen Al-Abdallat Layan Ismail Marah Alkderat Ro’ya Hzayen Yasmeen Al-Sheble Asem Mansour Maysa Al-Hussaini |
| author_sort | Mouness Obeidat |
| collection | DOAJ |
| description | IntroductionThe global cancer burden has been disproportionately shifting towards low- and middle-income countries (LMICs). Limited availability and accessibility to screening, treatment and surveillance, increase in the prevalence and lack of control of risk factors, and underdeveloped healthcare infrastructures have greatly contributed to the disparity in the global cancer burden.MethodsA retrospective cohort study was conducted that included adult and pediatric patients with an established diagnosis of Central Nervous System (CNS) tumors including brain or spinal tumors of which different demographic, clinical characteristics, and financial burden were presented.Results749 patients were included stemming from various countries in the Middle East/North Africa (MENA) region including Libya (34.2%), Palestine (19.8%), Iraq (15.4%), Syria (14.6%) Yemen (14.5%), and Sudan (1.5%). Most patients were adults (66%) with a median age of 34-year-old. 104 patients had died (13.9%), 80 patients were still alive (10.7%) and most of the patients (n= 565, 75.5%) were lost to follow-up. The added cost of managing these patients is 10,172,935 Jordanian Dinars (JOD), with King Hussein Cancer Foundation (KHCF) covering around 34.3% of the total cost.ConclusionOur study aimed at taking a closer look at patients coming from areas of conflict in the MENA region diagnosed and treated for CNS tumors at King Hussein Cancer Center (KHCC) over a 12-year period. It was found that even with the contributions of the Jordanian sources almost half of the patients were faced with the entire financial burden of treatment alone. |
| first_indexed | 2024-03-13T10:50:22Z |
| format | Article |
| id | doaj.art-88c959c79ac54ece85949bdc326dfef6 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-03-13T10:50:22Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-88c959c79ac54ece85949bdc326dfef62023-05-17T16:30:10ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-05-011310.3389/fonc.2023.10879871087987Central nervous system tumors in patients coming from areas of conflict in the Middle East/North Africa region: an experience from King Hussein Cancer CenterMouness Obeidat0Jamil Nazzal1Sarah Al Sharie2Ahmed Mahmoud Al-Azzam3Ahmad Maswadeh4Haneen Al-Abdallat5Layan Ismail6Marah Alkderat7Ro’ya Hzayen8Yasmeen Al-Sheble9Asem Mansour10Maysa Al-Hussaini11Department of Neurosurgery, King Hussein Cancer Center, Amman, JordanOffice of Scientific Affairs and Research, King Hussein Cancer Center, Amman, JordanFaculty of Medicine, Yarmouk University, Irbid, JordanOffice of Scientific Affairs and Research, King Hussein Cancer Center, Amman, JordanOffice of Scientific Affairs and Research, King Hussein Cancer Center, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanDepartment of Radiology, King Hussein Cancer Center, Amman, JordanDepartment of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, JordanIntroductionThe global cancer burden has been disproportionately shifting towards low- and middle-income countries (LMICs). Limited availability and accessibility to screening, treatment and surveillance, increase in the prevalence and lack of control of risk factors, and underdeveloped healthcare infrastructures have greatly contributed to the disparity in the global cancer burden.MethodsA retrospective cohort study was conducted that included adult and pediatric patients with an established diagnosis of Central Nervous System (CNS) tumors including brain or spinal tumors of which different demographic, clinical characteristics, and financial burden were presented.Results749 patients were included stemming from various countries in the Middle East/North Africa (MENA) region including Libya (34.2%), Palestine (19.8%), Iraq (15.4%), Syria (14.6%) Yemen (14.5%), and Sudan (1.5%). Most patients were adults (66%) with a median age of 34-year-old. 104 patients had died (13.9%), 80 patients were still alive (10.7%) and most of the patients (n= 565, 75.5%) were lost to follow-up. The added cost of managing these patients is 10,172,935 Jordanian Dinars (JOD), with King Hussein Cancer Foundation (KHCF) covering around 34.3% of the total cost.ConclusionOur study aimed at taking a closer look at patients coming from areas of conflict in the MENA region diagnosed and treated for CNS tumors at King Hussein Cancer Center (KHCC) over a 12-year period. It was found that even with the contributions of the Jordanian sources almost half of the patients were faced with the entire financial burden of treatment alone.https://www.frontiersin.org/articles/10.3389/fonc.2023.1087987/fullcancer care facilitiesoncology serviceareas of conflictMENA regionArab countriescentral nervous tumors |
| spellingShingle | Mouness Obeidat Jamil Nazzal Sarah Al Sharie Ahmed Mahmoud Al-Azzam Ahmad Maswadeh Haneen Al-Abdallat Layan Ismail Marah Alkderat Ro’ya Hzayen Yasmeen Al-Sheble Asem Mansour Maysa Al-Hussaini Central nervous system tumors in patients coming from areas of conflict in the Middle East/North Africa region: an experience from King Hussein Cancer Center Frontiers in Oncology cancer care facilities oncology service areas of conflict MENA region Arab countries central nervous tumors |
| title | Central nervous system tumors in patients coming from areas of conflict in the Middle East/North Africa region: an experience from King Hussein Cancer Center |
| title_full | Central nervous system tumors in patients coming from areas of conflict in the Middle East/North Africa region: an experience from King Hussein Cancer Center |
| title_fullStr | Central nervous system tumors in patients coming from areas of conflict in the Middle East/North Africa region: an experience from King Hussein Cancer Center |
| title_full_unstemmed | Central nervous system tumors in patients coming from areas of conflict in the Middle East/North Africa region: an experience from King Hussein Cancer Center |
| title_short | Central nervous system tumors in patients coming from areas of conflict in the Middle East/North Africa region: an experience from King Hussein Cancer Center |
| title_sort | central nervous system tumors in patients coming from areas of conflict in the middle east north africa region an experience from king hussein cancer center |
| topic | cancer care facilities oncology service areas of conflict MENA region Arab countries central nervous tumors |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1087987/full |
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