Sudden severe hyperammonemia and status epilepticus -a case report-

There are various causes to a low level of consciousness in patients in the intensive care unit. Neurological injury, infection, and metabolic disarray are considered as some of the causes. A 39 year-old female patient was transferred to our hospital with septic shock due to ascending colon perforat...

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Main Authors: Woo-Kyung Shin, Young-Eun Jang, Hannah Lee, Se-Hee Min, Ho-Geol Ryu
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2013-09-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kjae-65-262.pdf
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author Woo-Kyung Shin
Young-Eun Jang
Hannah Lee
Se-Hee Min
Ho-Geol Ryu
author_facet Woo-Kyung Shin
Young-Eun Jang
Hannah Lee
Se-Hee Min
Ho-Geol Ryu
author_sort Woo-Kyung Shin
collection DOAJ
description There are various causes to a low level of consciousness in patients in the intensive care unit. Neurological injury, infection, and metabolic disarray are considered as some of the causes. A 39 year-old female patient was transferred to our hospital with septic shock due to ascending colon perforation. The patient had previously received ovarian cancer surgery and a cycle of chemotherapy at another hospital. Emergent operation for colon perforation was successful. After the operation, she was treated in the intensive care unit for infectious and pulmonary complications. She suddenly showed deterioration in her level of consciousness and had a generalized seizure. At the time of her seizure, she had severe hyperammonemia. Brain CT showed severe cerebral edema that was absent in the CT scan taken 2 days before. Continuous renal replacement therapy was conducted but was ineffective in lowering the level of serum ammonia and the patient subsequently died.
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spelling doaj.art-88c98b5328d14e6cb4d9d841942a7efd2022-12-22T00:24:13ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632013-09-0165326226510.4097/kjae.2013.65.3.2627655Sudden severe hyperammonemia and status epilepticus -a case report-Woo-Kyung Shin0Young-Eun Jang1Hannah Lee2Se-Hee Min3Ho-Geol Ryu4Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.There are various causes to a low level of consciousness in patients in the intensive care unit. Neurological injury, infection, and metabolic disarray are considered as some of the causes. A 39 year-old female patient was transferred to our hospital with septic shock due to ascending colon perforation. The patient had previously received ovarian cancer surgery and a cycle of chemotherapy at another hospital. Emergent operation for colon perforation was successful. After the operation, she was treated in the intensive care unit for infectious and pulmonary complications. She suddenly showed deterioration in her level of consciousness and had a generalized seizure. At the time of her seizure, she had severe hyperammonemia. Brain CT showed severe cerebral edema that was absent in the CT scan taken 2 days before. Continuous renal replacement therapy was conducted but was ineffective in lowering the level of serum ammonia and the patient subsequently died.http://ekja.org/upload/pdf/kjae-65-262.pdfhyperammonemiaseizuresstatus epilepticus
spellingShingle Woo-Kyung Shin
Young-Eun Jang
Hannah Lee
Se-Hee Min
Ho-Geol Ryu
Sudden severe hyperammonemia and status epilepticus -a case report-
Korean Journal of Anesthesiology
hyperammonemia
seizures
status epilepticus
title Sudden severe hyperammonemia and status epilepticus -a case report-
title_full Sudden severe hyperammonemia and status epilepticus -a case report-
title_fullStr Sudden severe hyperammonemia and status epilepticus -a case report-
title_full_unstemmed Sudden severe hyperammonemia and status epilepticus -a case report-
title_short Sudden severe hyperammonemia and status epilepticus -a case report-
title_sort sudden severe hyperammonemia and status epilepticus a case report
topic hyperammonemia
seizures
status epilepticus
url http://ekja.org/upload/pdf/kjae-65-262.pdf
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