Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot Study
Background: Fibromyalgia (FM) is characterized by chronic widespread pain, as well as anxiety, sadness, and depression. These symptoms are present in most patients and have a negative impact on their daily, family, and social life. The role of neurotransmitters in the pathophysiology of FM has been...
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| Format: | Article |
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MDPI AG
2023-08-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/15/3469 |
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| author | María Victoria González-López-Arza José Vicente Triviño-Palomo Jesús Montanero-Fernández Elisa María Garrido-Ardila Blanca González-Sánchez María Jiménez-Palomares Juan Rodríguez-Mansilla |
| author_facet | María Victoria González-López-Arza José Vicente Triviño-Palomo Jesús Montanero-Fernández Elisa María Garrido-Ardila Blanca González-Sánchez María Jiménez-Palomares Juan Rodríguez-Mansilla |
| author_sort | María Victoria González-López-Arza |
| collection | DOAJ |
| description | Background: Fibromyalgia (FM) is characterized by chronic widespread pain, as well as anxiety, sadness, and depression. These symptoms are present in most patients and have a negative impact on their daily, family, and social life. The role of neurotransmitters in the pathophysiology of FM has been extensively discussed. The scientific evidence shows that levels of serotonin are decreased in patients with FM. Numerous studies support the beneficial effects that moderate wine consumption has on the body, with cardiovascular, endocrine, bone, and muscle improvements. Objective: The objective of this pilot study was to assess whether light consumption of red wine improves the main symptoms of FM. Methods: The study consisted of an experimental study with a control group with a total of 60 women diagnosed with FM following the American College of Rheumatology’s criteria. The experimental group ingested 15 g of alcohol per day, in the form of red wine, over a period of four weeks. The outcome measures were: the level of pain in tender points, sadness, anxiety, depression, and quality of life. The assessments tools were: tender point graphics, the visual analogue scale (for the assessment of pain and sadness), the Hamilton Anxiety Scale, the Hamilton Depression Rating Scale, and the Fibromyalgia Impact Questionnaire. The measurements were completed before and after the consumption of red wine. In addition, the differences between groups were evaluated in terms of drug consumption in the pre-intervention and follow-up phases. Results: Statistically significant improvements were obtained in the wine ingestion group for the variables of pain (<i>p</i> = 0.038), tender points (<i>p</i> < 0.001), and anxiety (<i>p</i> = 0.028). An improvement in the mean values was observed in favor of the experimental group for the variables of sadness, depression, and quality of life. The differences observed in the changes seen in the groups that were in favor of the wine ingestion group should not be attributed to the consumption of drugs but to the fact that the experimental group had a light intake of red wine. Conclusions: The results of this pilot study suggest a potential relationship between alcohol intake through the light consumption of red wine as part of the patients’ diet and the improvement of the main symptoms of fibromyalgia. Future studies are necessary to confirm these preliminary data; a bigger sample and a controlled diet should be considered, and the mechanisms through which improvements are achieved should be analyzed. |
| first_indexed | 2024-03-11T00:19:38Z |
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| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-11T00:19:38Z |
| publishDate | 2023-08-01 |
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| series | Nutrients |
| spelling | doaj.art-88ca4ae1e0524aea81a4789a0c28cc4c2023-11-18T23:24:59ZengMDPI AGNutrients2072-66432023-08-011515346910.3390/nu15153469Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot StudyMaría Victoria González-López-Arza0José Vicente Triviño-Palomo1Jesús Montanero-Fernández2Elisa María Garrido-Ardila3Blanca González-Sánchez4María Jiménez-Palomares5Juan Rodríguez-Mansilla6ADOLOR Research Group, Department of Medical-Surgical Therapy, Faculty of Medicine and Health Sciences, Extremadura University, 06006 Badajoz, SpainADOLOR Research Group, Department of Medical-Surgical Therapy, Faculty of Medicine and Health Sciences, Extremadura University, 06006 Badajoz, SpainMathematics Department, Faculty of Medicine and Health Sciences, Extremadura University, 06006 Badajoz, SpainADOLOR Research Group, Department of Medical-Surgical Therapy, Faculty of Medicine and Health Sciences, Extremadura University, 06006 Badajoz, SpainADOLOR Research Group, Department of Medical-Surgical Therapy, Faculty of Medicine and Health Sciences, Extremadura University, 06006 Badajoz, SpainADOLOR Research Group, Department of Medical-Surgical Therapy, Faculty of Medicine and Health Sciences, Extremadura University, 06006 Badajoz, SpainADOLOR Research Group, Department of Medical-Surgical Therapy, Faculty of Medicine and Health Sciences, Extremadura University, 06006 Badajoz, SpainBackground: Fibromyalgia (FM) is characterized by chronic widespread pain, as well as anxiety, sadness, and depression. These symptoms are present in most patients and have a negative impact on their daily, family, and social life. The role of neurotransmitters in the pathophysiology of FM has been extensively discussed. The scientific evidence shows that levels of serotonin are decreased in patients with FM. Numerous studies support the beneficial effects that moderate wine consumption has on the body, with cardiovascular, endocrine, bone, and muscle improvements. Objective: The objective of this pilot study was to assess whether light consumption of red wine improves the main symptoms of FM. Methods: The study consisted of an experimental study with a control group with a total of 60 women diagnosed with FM following the American College of Rheumatology’s criteria. The experimental group ingested 15 g of alcohol per day, in the form of red wine, over a period of four weeks. The outcome measures were: the level of pain in tender points, sadness, anxiety, depression, and quality of life. The assessments tools were: tender point graphics, the visual analogue scale (for the assessment of pain and sadness), the Hamilton Anxiety Scale, the Hamilton Depression Rating Scale, and the Fibromyalgia Impact Questionnaire. The measurements were completed before and after the consumption of red wine. In addition, the differences between groups were evaluated in terms of drug consumption in the pre-intervention and follow-up phases. Results: Statistically significant improvements were obtained in the wine ingestion group for the variables of pain (<i>p</i> = 0.038), tender points (<i>p</i> < 0.001), and anxiety (<i>p</i> = 0.028). An improvement in the mean values was observed in favor of the experimental group for the variables of sadness, depression, and quality of life. The differences observed in the changes seen in the groups that were in favor of the wine ingestion group should not be attributed to the consumption of drugs but to the fact that the experimental group had a light intake of red wine. Conclusions: The results of this pilot study suggest a potential relationship between alcohol intake through the light consumption of red wine as part of the patients’ diet and the improvement of the main symptoms of fibromyalgia. Future studies are necessary to confirm these preliminary data; a bigger sample and a controlled diet should be considered, and the mechanisms through which improvements are achieved should be analyzed.https://www.mdpi.com/2072-6643/15/15/3469fibromyalgiawinepainanxietyfibromyalgia impact questionnaire |
| spellingShingle | María Victoria González-López-Arza José Vicente Triviño-Palomo Jesús Montanero-Fernández Elisa María Garrido-Ardila Blanca González-Sánchez María Jiménez-Palomares Juan Rodríguez-Mansilla Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot Study Nutrients fibromyalgia wine pain anxiety fibromyalgia impact questionnaire |
| title | Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot Study |
| title_full | Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot Study |
| title_fullStr | Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot Study |
| title_full_unstemmed | Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot Study |
| title_short | Benefits of the Light Consumption of Red Wine in Pain, Tender Points, and Anxiety in Women with Fibromyalgia: A Pilot Study |
| title_sort | benefits of the light consumption of red wine in pain tender points and anxiety in women with fibromyalgia a pilot study |
| topic | fibromyalgia wine pain anxiety fibromyalgia impact questionnaire |
| url | https://www.mdpi.com/2072-6643/15/15/3469 |
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