Kansuinine A Ameliorates Atherosclerosis and Human Aortic Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Production and Suppressing IKKβ/IκBα/NF-κB Signaling

Kansuinine A Ameliorates Atherosclerosis and Human Aortic Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Production and Suppressing IKKβ/IκBα/NF-κB Signaling

Reactive oxygen species (ROS)-induced vascular endothelial cell apoptosis is strongly associated with atherosclerosis progression. Herein, we aimed to examine whether Kansuinine A (KA), extracted from <i>Euphorbia kansui</i> L., prevents atherosclerosis development in a mouse model and i...

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Bibliographic Details
Main Authors:	Chen-Sheng Chen, Bo-Yi Pan, Ping-Hsuan Tsai, Fang-Yu Chen, Wen-Chin Yang, Ming-Yi Shen
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Series:	International Journal of Molecular Sciences
Subjects:	Kansuinine A anti-atherogenic drug atherosclerosis reactive oxygen species human aortic endothelial cells
Online Access:	https://www.mdpi.com/1422-0067/22/19/10309

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