MASQC: Next Generation Sequencing Assists Third Generation Sequencing for Quality Control in N6-Methyladenine DNA Identification

MASQC: Next Generation Sequencing Assists Third Generation Sequencing for Quality Control in N6-Methyladenine DNA Identification

DNA N6-methyladenine (6mA) modification has been discovered as the most prevalent DNA modification in prokaryotes and eukaryotes, involving gene expression, DNA replication and repair, and host-pathogen interactions. Single-molecule real-time sequencing (SMRT-seq) can detect 6mA events in prokaryoti...

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Bibliographic Details
Main Authors: Siqian Yang, Yaoxin Wang, Ying Chen, Qi Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Genetics
Subjects:
DNA N6-methyladenine
MeDIP-seq
SMRT-seq
eukaryotes
prokaryotes
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00269/full

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