Poxvirus Viability and Signatures in Historical Relics
Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence. Experimental data to address the long-term s...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2014-02-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/20/2/13-1098_article |
| _version_ | 1818756239620833280 |
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| author | Andrea M. McCollum Yu Li Kimberly Wilkins Kevin L. Karem Whitni B. Davidson Christopher D. Paddock Mary G. Reynolds Inger K. Damon |
| author_facet | Andrea M. McCollum Yu Li Kimberly Wilkins Kevin L. Karem Whitni B. Davidson Christopher D. Paddock Mary G. Reynolds Inger K. Damon |
| author_sort | Andrea M. McCollum |
| collection | DOAJ |
| description | Although it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence. Experimental data to address the long-term stability and viability of the virus are limited. There are several instances of well-preserved corpses and tissues that have been examined for poxvirus viability and viral DNA. These historical specimens cause concern for potential exposures, and each situation should be approached cautiously and independently with the available information. Nevertheless, these specimens provide information on the history of a major disease and vaccination against it.
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| first_indexed | 2024-12-18T05:51:53Z |
| format | Article |
| id | doaj.art-88d38ca4b6e74601a722b2d27817cf1f |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-18T05:51:53Z |
| publishDate | 2014-02-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-88d38ca4b6e74601a722b2d27817cf1f2022-12-21T21:18:54ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-02-0120217718410.3201/eid2002.131098Poxvirus Viability and Signatures in Historical RelicsAndrea M. McCollumYu LiKimberly WilkinsKevin L. KaremWhitni B. DavidsonChristopher D. PaddockMary G. ReynoldsInger K. DamonAlthough it has been >30 years since the eradication of smallpox, the unearthing of well-preserved tissue material in which the virus may reside has called into question the viability of variola virus decades or centuries after its original occurrence. Experimental data to address the long-term stability and viability of the virus are limited. There are several instances of well-preserved corpses and tissues that have been examined for poxvirus viability and viral DNA. These historical specimens cause concern for potential exposures, and each situation should be approached cautiously and independently with the available information. Nevertheless, these specimens provide information on the history of a major disease and vaccination against it. Download MP3 Length: 0:52https://wwwnc.cdc.gov/eid/article/20/2/13-1098_articlesmallpoxsmallpox viruspoxvirusvirusesvariolaorthopoxvirus |
| spellingShingle | Andrea M. McCollum Yu Li Kimberly Wilkins Kevin L. Karem Whitni B. Davidson Christopher D. Paddock Mary G. Reynolds Inger K. Damon Poxvirus Viability and Signatures in Historical Relics Emerging Infectious Diseases smallpox smallpox virus poxvirus viruses variola orthopoxvirus |
| title | Poxvirus Viability and Signatures in Historical Relics |
| title_full | Poxvirus Viability and Signatures in Historical Relics |
| title_fullStr | Poxvirus Viability and Signatures in Historical Relics |
| title_full_unstemmed | Poxvirus Viability and Signatures in Historical Relics |
| title_short | Poxvirus Viability and Signatures in Historical Relics |
| title_sort | poxvirus viability and signatures in historical relics |
| topic | smallpox smallpox virus poxvirus viruses variola orthopoxvirus |
| url | https://wwwnc.cdc.gov/eid/article/20/2/13-1098_article |
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