Complement Anaphylatoxins and Inflammatory Cytokines as Prognostic Markers for COVID-19 Severity and In-Hospital Mortality

Complement Anaphylatoxins and Inflammatory Cytokines as Prognostic Markers for COVID-19 Severity and In-Hospital Mortality

COVID-19 severity due to innate immunity dysregulation accounts for prolonged hospitalization, critical complications, and mortality. Severe SARS-CoV-2 infections involve the complement pathway activation for cytokine storm development. Nevertheless, the role of complement in COVID-19 immunopatholog...

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Bibliographic Details
Main Authors: Bandar Alosaimi, Ayman Mubarak, Maaweya E. Hamed, Abdullah Z. Almutairi, Ahmed A. Alrashed, Abdullah AlJuryyan, Mushira Enani, Faris Q. Alenzi, Wael Alturaiki
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS‐CoV‐2
complement anaphylatoxins
inflammatory cytokines
in-hospital mortality
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.668725/full

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