Identification of 1, 2, 4-Triazine and Its Derivatives Against Lanosterol 14-Demethylase (CYP51) Property of Candida albicans: Influence on the Development of New Antifungal Therapeutic Strategies

Identification of 1, 2, 4-Triazine and Its Derivatives Against Lanosterol 14-Demethylase (CYP51) Property of Candida albicans: Influence on the Development of New Antifungal Therapeutic Strategies

This research aims to find out whether the 1, 2, 4-triazine and its derivatives have antifungal effects and can protect humans from infection with Candida albicans. Molecular docking and molecular dynamic simulation are widely used in modern drug design to target a particular protein with a ligand....

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Bibliographic Details
Main Authors: Abhishek Kumar Verma, Aarfah Majid, Md. Shahadat Hossain, SK. Faisal Ahmed, Mohammad Ashid, Ali Asger Bhojiya, Sudhir K. Upadhyay, Naveen Kumar Vishvakarma, Mudassir Alam
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Medical Technology
Subjects:
1
2
4-triazine
Lanosterol 14-demethylase (CYP51)
drug resistance
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fmedt.2022.845322/full

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