Comparative rate and risk factors of recurrent urethral stricture during different surgical procedures
<p align="LEFT"><strong>Objective</strong> – <span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">to identify the major risk factors leading to worse results of surg...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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ABV-press
2014-11-01
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| Series: | Андрология и генитальная хирургия |
| Subjects: | |
| Online Access: | http://agx.abvpress.ru/index.php/jour/article/view/13 |
| _version_ | 1798004808248983552 |
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| author | D. Yu. Pushkar A. V. Zhivov O. B. Loran A. V. Karpovich M. R. Bagaudinov M. R.M. Ismailov |
| author_facet | D. Yu. Pushkar A. V. Zhivov O. B. Loran A. V. Karpovich M. R. Bagaudinov M. R.M. Ismailov |
| author_sort | D. Yu. Pushkar |
| collection | DOAJ |
| description | <p align="LEFT"><strong>Objective</strong> – <span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">to identify the major risk factors leading to worse results of surgical treatment in patients with urethral stricture.</span></span></p><strong><em><em></em></em></strong><p align="LEFT"><strong>Subjects and methods. </strong><span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">Two hundred and forty-eight patients with urethral stricture underwent different surgical interventions: internal optical </span></span>urethrotomy (IOU) for strictures of different portions of the urethra in 157 patients (the operation was made once in 121 patients, twice in 24 patients, and thrice or more in 12); replacement urethroplasty using a buccal mucosa graft for strictures of the anterior urethra in 46 patients; Turner-Warwick’s anastomotic urethroplasty modified by Webster for strictures (distraction defects) of the posterior urethra in 45 patients. The results of surgical treatment were studied using urethrography, uroflowmetry, urethrocystoscopy, the international prostate symptom score, quality of life (QoL) questionnaire, and the international index of erectile function (IIEF) questionnaire. The role of risk factors for postoperative recurrent urethral stricture was assessed by univariate and multivariate analyses.</p><strong><em><em></em></em></strong><p align="LEFT"><strong>Results. </strong><span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">The rate of recurrent urethral stricture after IOU was 66.9 % (59.5, 87.5, and 100 % after the first, second, third or more subsequent </span></span>operations, respectively; 12.1 % after all types of urethroplasty, 15.2 % after augmentation urethroplasty, and 8.9 % after anastomotic urethroplasty. The major risk factors of recurrent urethral stricture after IOU were recognized to be the location of urethral stricture in the penile or bulbomembranous portions, a urethral stricture length of > 1 cm, severe urethral lumen narrowing, and performance of 2 or more operations; those after augmentation urethroplasty were previous ineffective treatment, a stricture length of > 4 cm, lichen sclerosus, and smoking; those after anastomotic urethroplasty were previous ineffective treatment, smoking, and a stricture length of > 4 cm.</p><p align="LEFT"><strong>Conclusion</strong>. T<span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">he results of the investigation have shown that only pathogenetically grounded treatments for stricture allow their high efficiency </span></span>to be achieved.</p><em></em> |
| first_indexed | 2024-04-11T12:29:13Z |
| format | Article |
| id | doaj.art-88e23836433e4048830a55d226abe3be |
| institution | Directory Open Access Journal |
| issn | 2070-9781 |
| language | Russian |
| last_indexed | 2024-04-11T12:29:13Z |
| publishDate | 2014-11-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Андрология и генитальная хирургия |
| spelling | doaj.art-88e23836433e4048830a55d226abe3be2022-12-22T04:23:50ZrusABV-pressАндрология и генитальная хирургия2070-97812014-11-0113437447Comparative rate and risk factors of recurrent urethral stricture during different surgical proceduresD. Yu. Pushkar0A. V. Zhivov1O. B. Loran2A. V. Karpovich3M. R. Bagaudinov4M. R.M. Ismailov5A.I. Evdokimov Moscow State University of Medicine and DentistryA.I. Evdokimov Moscow State University of Medicine and Dentistry; OOO MEDEM International ClinicRussian Medical Academy of Postgraduate EducationA.I. Evdokimov Moscow State University of Medicine and DentistryA.I. Evdokimov Moscow State University of Medicine and DentistryA.I. Evdokimov Moscow State University of Medicine and Dentistry<p align="LEFT"><strong>Objective</strong> – <span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">to identify the major risk factors leading to worse results of surgical treatment in patients with urethral stricture.</span></span></p><strong><em><em></em></em></strong><p align="LEFT"><strong>Subjects and methods. </strong><span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">Two hundred and forty-eight patients with urethral stricture underwent different surgical interventions: internal optical </span></span>urethrotomy (IOU) for strictures of different portions of the urethra in 157 patients (the operation was made once in 121 patients, twice in 24 patients, and thrice or more in 12); replacement urethroplasty using a buccal mucosa graft for strictures of the anterior urethra in 46 patients; Turner-Warwick’s anastomotic urethroplasty modified by Webster for strictures (distraction defects) of the posterior urethra in 45 patients. The results of surgical treatment were studied using urethrography, uroflowmetry, urethrocystoscopy, the international prostate symptom score, quality of life (QoL) questionnaire, and the international index of erectile function (IIEF) questionnaire. The role of risk factors for postoperative recurrent urethral stricture was assessed by univariate and multivariate analyses.</p><strong><em><em></em></em></strong><p align="LEFT"><strong>Results. </strong><span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">The rate of recurrent urethral stricture after IOU was 66.9 % (59.5, 87.5, and 100 % after the first, second, third or more subsequent </span></span>operations, respectively; 12.1 % after all types of urethroplasty, 15.2 % after augmentation urethroplasty, and 8.9 % after anastomotic urethroplasty. The major risk factors of recurrent urethral stricture after IOU were recognized to be the location of urethral stricture in the penile or bulbomembranous portions, a urethral stricture length of > 1 cm, severe urethral lumen narrowing, and performance of 2 or more operations; those after augmentation urethroplasty were previous ineffective treatment, a stricture length of > 4 cm, lichen sclerosus, and smoking; those after anastomotic urethroplasty were previous ineffective treatment, smoking, and a stricture length of > 4 cm.</p><p align="LEFT"><strong>Conclusion</strong>. T<span style="font-family: NewtonC-Italic; font-size: xx-small;"><span style="font-family: NewtonC-Italic; font-size: xx-small;">he results of the investigation have shown that only pathogenetically grounded treatments for stricture allow their high efficiency </span></span>to be achieved.</p><em></em>http://agx.abvpress.ru/index.php/jour/article/view/13urethral stricture, internal optical urethrotomy, urethroplasty, recurrent stricture, risk factors |
| spellingShingle | D. Yu. Pushkar A. V. Zhivov O. B. Loran A. V. Karpovich M. R. Bagaudinov M. R.M. Ismailov Comparative rate and risk factors of recurrent urethral stricture during different surgical procedures Андрология и генитальная хирургия urethral stricture, internal optical urethrotomy, urethroplasty, recurrent stricture, risk factors |
| title | Comparative rate and risk factors of recurrent urethral stricture during different surgical procedures |
| title_full | Comparative rate and risk factors of recurrent urethral stricture during different surgical procedures |
| title_fullStr | Comparative rate and risk factors of recurrent urethral stricture during different surgical procedures |
| title_full_unstemmed | Comparative rate and risk factors of recurrent urethral stricture during different surgical procedures |
| title_short | Comparative rate and risk factors of recurrent urethral stricture during different surgical procedures |
| title_sort | comparative rate and risk factors of recurrent urethral stricture during different surgical procedures |
| topic | urethral stricture, internal optical urethrotomy, urethroplasty, recurrent stricture, risk factors |
| url | http://agx.abvpress.ru/index.php/jour/article/view/13 |
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