Opposing Spatially Segregated Function of Endogenous GDNF-RET Signaling in Cocaine Addiction

Opposing Spatially Segregated Function of Endogenous GDNF-RET Signaling in Cocaine Addiction

Cocaine addiction is a serious condition with potentially lethal complications and no current pharmacological approaches towards treatment. Perturbations of the mesolimbic dopamine system are crucial to the establishment of cocaine-induced conditioned place preference and reward. As a potent neurotr...

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Bibliographic Details
Main Authors: Daniel R. Garton, Giorgio Turconi, Vilma Iivanainen, Jaan-Olle Andressoo
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
addiction
dopamine
GDNF
GFRa1
RET
BDNF
Online Access:https://www.mdpi.com/2218-273X/13/5/761

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