A strategy of novel molecular hydrogen-producing antioxidative auxiliary system improves virus production in cell bioreactor

Abstract In the increasing demand for virus vaccines, large-scale production of safe, efficient, and economical viral antigens has become a significant challenge. High-cell-density manufacturing processes are the most commonly used to produce vaccine antigens and protein drugs. However, the cellular...

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Bibliographic Details
Main Authors: Yu-Jing Zeng, Min-Kung Hsu, Jia-Rong Cai, Hsian-Yu Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-54847-7