IMPACT OF MULTIPLE BIRTHS ON THE OUTCOME IN EXTREMELY LOW BIRTH WEIGHT NEWBORNS
Objective: To evaluate the outcome of the extremely low birth weight newborns (ELBWNs) from single and twin pregnancies. Material and methods: The study lasts from 2005 to 2017 and includes all life born ELBWNs treated in University Hospital, Pleven, Bulgaria. Patients' groups: singletons (1)...
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| Format: | Article |
| Language: | English |
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Peytchinski Publishing
2021-09-01
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| Series: | Journal of IMAB |
| Subjects: | |
| Online Access: | https://www.journal-imab-bg.org/issues-2021/issue3/2021vol27-issue3-3985-3991.pdf |
| _version_ | 1818443856532733952 |
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| author | Victoria Atanasova Petar Ivanov Elitsa Gyokova Desislava Georgieva Lyuben Veskov |
| author_facet | Victoria Atanasova Petar Ivanov Elitsa Gyokova Desislava Georgieva Lyuben Veskov |
| author_sort | Victoria Atanasova |
| collection | DOAJ |
| description | Objective: To evaluate the outcome of the extremely low birth weight newborns (ELBWNs) from single and twin pregnancies.
Material and methods: The study lasts from 2005 to 2017 and includes all life born ELBWNs treated in University Hospital, Pleven, Bulgaria. Patients' groups: singletons (1) and twins (2); twins conceived naturally(2.1) and after assisted reproductive technologies – ART(2.2).
Results: One hundred and eighty two (182) ELBWNs are examined, 65 (35.7%) of them are twins. The twins, compared to singletons, are significantly more often conceived by ART (47.7 vs 4.3%, p<0.001) and significantly more rarely infected prenatally (18 vs 41%, p 0.002). The survival rate is 51.3% for singletons and 56.6% for twins, NS.
Survived twins (n 37) achieve later their optimal nutritive tolerance (30±11 vs 25±10 days, p 0.046), require more blood transfusions (3.6±1.9 vs 2.6±1.8 per patient, p 0.009) and longer mechanical ventilation (16±15 vs 9±12 days, p 0.03) than survival singletons (n 60).
The twins suffer more often from intraventricular haemorrhage (46 vs 18%, p 0.004), patent ductus arteriosus (35 vs 15%, p 0.02) and long-term complications (51 vs 30%, p 0.04) than singletons.
ART-twins (n 31)compared to the subgroup 2.1 (n 34) are more frequently intubated in the delivery room (81 vs. 50%, p 0.01)but suffer less frequently from nosocomial infections (53 vs. 85%, p 0.03).
Conclusions: According to our data, ELBW-twins frequently suffer from respiratory, haemorrhagic, and gastrointestinal problems than ELBW-singletons, resulting in more long-term complications.
Our study proves that ART does not influence the outcome in multiples. |
| first_indexed | 2024-12-14T19:06:41Z |
| format | Article |
| id | doaj.art-88f05edd61e74c5ba2bfd60cb8a5b4f8 |
| institution | Directory Open Access Journal |
| issn | 1312-773X |
| language | English |
| last_indexed | 2024-12-14T19:06:41Z |
| publishDate | 2021-09-01 |
| publisher | Peytchinski Publishing |
| record_format | Article |
| series | Journal of IMAB |
| spelling | doaj.art-88f05edd61e74c5ba2bfd60cb8a5b4f82022-12-21T22:50:50ZengPeytchinski PublishingJournal of IMAB1312-773X2021-09-012733985399110.5272/jimab.2021273.3985IMPACT OF MULTIPLE BIRTHS ON THE OUTCOME IN EXTREMELY LOW BIRTH WEIGHT NEWBORNSVictoria Atanasova0https://orcid.org/0000-0003-2099-2142Petar Ivanov1https://orcid.org/0000-0002-7754-9128Elitsa Gyokova2https://orcid.org/0000-0003-4007-7961Desislava Georgieva3https://orcid.org/0000-0001-9045-701XLyuben Veskov4https://orcid.org/0000-0003-4392-8717Clinic of Neonatology, UMHAT 'Dr. G. Stranski’, Pleven, Bulgaria.Clinical Institute for Reproductive Medicine, Pleven, Bulgaria.Department of Obstetrics and Gynecology, Medical University of Pleven, Bulgaria.Home of medical and social care for children, Pleven, Bulgaria.Clinic of Neonatology, UMHAT 'Dr. G. Stranski’, Pleven, Bulgaria.Objective: To evaluate the outcome of the extremely low birth weight newborns (ELBWNs) from single and twin pregnancies. Material and methods: The study lasts from 2005 to 2017 and includes all life born ELBWNs treated in University Hospital, Pleven, Bulgaria. Patients' groups: singletons (1) and twins (2); twins conceived naturally(2.1) and after assisted reproductive technologies – ART(2.2). Results: One hundred and eighty two (182) ELBWNs are examined, 65 (35.7%) of them are twins. The twins, compared to singletons, are significantly more often conceived by ART (47.7 vs 4.3%, p<0.001) and significantly more rarely infected prenatally (18 vs 41%, p 0.002). The survival rate is 51.3% for singletons and 56.6% for twins, NS. Survived twins (n 37) achieve later their optimal nutritive tolerance (30±11 vs 25±10 days, p 0.046), require more blood transfusions (3.6±1.9 vs 2.6±1.8 per patient, p 0.009) and longer mechanical ventilation (16±15 vs 9±12 days, p 0.03) than survival singletons (n 60). The twins suffer more often from intraventricular haemorrhage (46 vs 18%, p 0.004), patent ductus arteriosus (35 vs 15%, p 0.02) and long-term complications (51 vs 30%, p 0.04) than singletons. ART-twins (n 31)compared to the subgroup 2.1 (n 34) are more frequently intubated in the delivery room (81 vs. 50%, p 0.01)but suffer less frequently from nosocomial infections (53 vs. 85%, p 0.03). Conclusions: According to our data, ELBW-twins frequently suffer from respiratory, haemorrhagic, and gastrointestinal problems than ELBW-singletons, resulting in more long-term complications. Our study proves that ART does not influence the outcome in multiples.https://www.journal-imab-bg.org/issues-2021/issue3/2021vol27-issue3-3985-3991.pdfnewborntwinsextremely low birth weightassisted reproductive technologyfollow-up |
| spellingShingle | Victoria Atanasova Petar Ivanov Elitsa Gyokova Desislava Georgieva Lyuben Veskov IMPACT OF MULTIPLE BIRTHS ON THE OUTCOME IN EXTREMELY LOW BIRTH WEIGHT NEWBORNS Journal of IMAB newborn twins extremely low birth weight assisted reproductive technology follow-up |
| title | IMPACT OF MULTIPLE BIRTHS ON THE OUTCOME IN EXTREMELY LOW BIRTH WEIGHT NEWBORNS |
| title_full | IMPACT OF MULTIPLE BIRTHS ON THE OUTCOME IN EXTREMELY LOW BIRTH WEIGHT NEWBORNS |
| title_fullStr | IMPACT OF MULTIPLE BIRTHS ON THE OUTCOME IN EXTREMELY LOW BIRTH WEIGHT NEWBORNS |
| title_full_unstemmed | IMPACT OF MULTIPLE BIRTHS ON THE OUTCOME IN EXTREMELY LOW BIRTH WEIGHT NEWBORNS |
| title_short | IMPACT OF MULTIPLE BIRTHS ON THE OUTCOME IN EXTREMELY LOW BIRTH WEIGHT NEWBORNS |
| title_sort | impact of multiple births on the outcome in extremely low birth weight newborns |
| topic | newborn twins extremely low birth weight assisted reproductive technology follow-up |
| url | https://www.journal-imab-bg.org/issues-2021/issue3/2021vol27-issue3-3985-3991.pdf |
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