Acceleration of bone union by in situ-formed hydrogel containing bone morphogenetic protein-2 in a mouse refractory fracture model

Acceleration of bone union by in situ-formed hydrogel containing bone morphogenetic protein-2 in a mouse refractory fracture model

Abstract Background An enzymatic crosslinking strategy using hydrogen peroxide and horseradish peroxidase is receiving increasing attention for application with in situ-formed hydrogels (IFHs). Several studies have reported the application of IFHs in cell delivery and tissue engineering. IFHs may al...

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Bibliographic Details
Main Authors: Shintaro Shoji, Kentaro Uchida, Wataru Satio, Hiroyuki Sekiguchi, Gen Inoue, Masayuki Miyagi, Ken Takata, Yuji Yokozeki, Masashi Takaso
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
In situ-formed hydrogels
Hyaluronic acid
Bone morphogenetic protein
Refractory fracture
Online Access:http://link.springer.com/article/10.1186/s13018-020-01953-7

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