Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more?

Niclosamide in prostate cancer: An inhibitor of AR-V7, a mitochondrial uncoupler, or more?

A recent phase Ib study investigating the use of reformulated niclosamide in combination with abiraterone and prednisone in patients with castration-resistant prostate cancer (CRPC) demonstrated encouraging preliminary efficacy with low toxicity. Preclinical studies have reported that niclosamide at...

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Bibliographic Details
Main Author:	Minas Sakellakis
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Series:	Cancer Treatment and Research Communications
Subjects:	Niclosamide Prostate cancer Uncouplers AR-V7 Inhibitor
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468294223000060

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