A case of subclinical hypothyroidism with cerebellar ataxia

Hypothyroidism is a common condition, the symptoms and signs of which vary with the duration and magnitude of thyroid hormone deficiency. Hypothyroidism can have rare neurologic problems such as reversible cerebellar ataxia. Subclinical hypothyroidism refers to biochemical evidence of thyroid hormon...

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Main Authors: Shwet Sabnis, Tushar K Biswas
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:MGM Journal of Medical Sciences
Subjects:
Online Access:http://www.mgmjms.com/article.asp?issn=2347-7946;year=2022;volume=9;issue=2;spage=250;epage=253;aulast=Sabnis
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author Shwet Sabnis
Tushar K Biswas
author_facet Shwet Sabnis
Tushar K Biswas
author_sort Shwet Sabnis
collection DOAJ
description Hypothyroidism is a common condition, the symptoms and signs of which vary with the duration and magnitude of thyroid hormone deficiency. Hypothyroidism can have rare neurologic problems such as reversible cerebellar ataxia. Subclinical hypothyroidism refers to biochemical evidence of thyroid hormone deficiency in patients who have few or no apparent clinical features of hypothyroidism. Here, we present a case of a 70-year-old woman with complaints of giddiness and unsteadiness of 6 months’ duration. Subsequent evaluation revealed titubation, broad-based reeling gait, and dysarthria. A MRI of the brain showed diffuse moderate cerebral atrophy with periventricular ischemic white matter changes and normal cerebellum. Further investigations revealed evidence of subclinical hypothyroidism. The patient was started on oral thyroxine supplements with a relief of symptoms following 3 weeks after the initiation of treatment and a complete recovery from symptoms after about 3 months of the initiation of treatment. The association of cerebellar involvement at the stage of subclinical hypothyroidism is a rare finding, making the case academically interesting.
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spelling doaj.art-88fcd8dca6d3411d9d7ffe67ea8e1f472022-12-22T00:42:58ZengWolters Kluwer Medknow PublicationsMGM Journal of Medical Sciences2347-79462347-79622022-01-019225025310.4103/mgmj.mgmj_82_21A case of subclinical hypothyroidism with cerebellar ataxiaShwet SabnisTushar K BiswasHypothyroidism is a common condition, the symptoms and signs of which vary with the duration and magnitude of thyroid hormone deficiency. Hypothyroidism can have rare neurologic problems such as reversible cerebellar ataxia. Subclinical hypothyroidism refers to biochemical evidence of thyroid hormone deficiency in patients who have few or no apparent clinical features of hypothyroidism. Here, we present a case of a 70-year-old woman with complaints of giddiness and unsteadiness of 6 months’ duration. Subsequent evaluation revealed titubation, broad-based reeling gait, and dysarthria. A MRI of the brain showed diffuse moderate cerebral atrophy with periventricular ischemic white matter changes and normal cerebellum. Further investigations revealed evidence of subclinical hypothyroidism. The patient was started on oral thyroxine supplements with a relief of symptoms following 3 weeks after the initiation of treatment and a complete recovery from symptoms after about 3 months of the initiation of treatment. The association of cerebellar involvement at the stage of subclinical hypothyroidism is a rare finding, making the case academically interesting.http://www.mgmjms.com/article.asp?issn=2347-7946;year=2022;volume=9;issue=2;spage=250;epage=253;aulast=Sabniscerebellar ataxiasubclinical hypothyroidismthyroxine
spellingShingle Shwet Sabnis
Tushar K Biswas
A case of subclinical hypothyroidism with cerebellar ataxia
MGM Journal of Medical Sciences
cerebellar ataxia
subclinical hypothyroidism
thyroxine
title A case of subclinical hypothyroidism with cerebellar ataxia
title_full A case of subclinical hypothyroidism with cerebellar ataxia
title_fullStr A case of subclinical hypothyroidism with cerebellar ataxia
title_full_unstemmed A case of subclinical hypothyroidism with cerebellar ataxia
title_short A case of subclinical hypothyroidism with cerebellar ataxia
title_sort case of subclinical hypothyroidism with cerebellar ataxia
topic cerebellar ataxia
subclinical hypothyroidism
thyroxine
url http://www.mgmjms.com/article.asp?issn=2347-7946;year=2022;volume=9;issue=2;spage=250;epage=253;aulast=Sabnis
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