Zonisamide Ameliorates Microglial Mitochondriopathy in Parkinson’s Disease Models

Zonisamide Ameliorates Microglial Mitochondriopathy in Parkinson’s Disease Models

Mitochondrial dysfunction and exacerbated neuroinflammation are critical factors in the pathogenesis of both familial and non-familial forms of Parkinson’s disease (PD). This study aims to understand the possible ameliorative effects of zonisamide on microglial mitochondrial dysfunction in PD. We pr...

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Bibliographic Details
Main Authors: Satoshi Tada, Mohammed E. Choudhury, Madoka Kubo, Rina Ando, Junya Tanaka, Masahiro Nagai
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Brain Sciences
Subjects:
zonisamide
microglia
inflammation
mitochondria
Parkinson’s disease
Online Access:https://www.mdpi.com/2076-3425/12/2/268

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