Metastatic basal cell carcinoma: A report of two cases and a review of the literature

Basal cell carcinomas (BCCs) are among the most common non-melanoma skin cancers in the world. However, given their slowly progressive nature, metastatic BCCs are a relatively uncommon entity. Below, we discuss two separate cases of metastatic BCC that we encountered in our clinical practic...

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Main Authors: Claire Quigley, Siona Ni Raghallaigh
Format: Article
Language:English
Published: Our Dermatology Online 2022-01-01
Series:Nasza Dermatologia Online
Online Access:http://www.odermatol.com/issue-in-html/2022-1-18-metastatic_bcc/
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author Claire Quigley
Siona Ni Raghallaigh
author_facet Claire Quigley
Siona Ni Raghallaigh
author_sort Claire Quigley
collection DOAJ
description Basal cell carcinomas (BCCs) are among the most common non-melanoma skin cancers in the world. However, given their slowly progressive nature, metastatic BCCs are a relatively uncommon entity. Below, we discuss two separate cases of metastatic BCC that we encountered in our clinical practice. The first is the case of a 57-year-old male with a right cheek BCC and bilateral pulmonary metastases. The second is the case of a 71-year-old male who also presented with a right BCC and pulmonary metastases. We discuss their altered clinical courses. We also conducted a review of the literature focusing on the use of the relatively novel hedgehog inhibitors as a treatment option for individuals diagnosed with metastatic BCC.
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spelling doaj.art-890264ca299e420a8473e7759ec4811d2022-12-25T15:58:38ZengOur Dermatology OnlineNasza Dermatologia Online2081-93902022-01-01131737610.7241/ourd.20221.18Metastatic basal cell carcinoma: A report of two cases and a review of the literatureClaire QuigleySiona Ni Raghallaigh Basal cell carcinomas (BCCs) are among the most common non-melanoma skin cancers in the world. However, given their slowly progressive nature, metastatic BCCs are a relatively uncommon entity. Below, we discuss two separate cases of metastatic BCC that we encountered in our clinical practice. The first is the case of a 57-year-old male with a right cheek BCC and bilateral pulmonary metastases. The second is the case of a 71-year-old male who also presented with a right BCC and pulmonary metastases. We discuss their altered clinical courses. We also conducted a review of the literature focusing on the use of the relatively novel hedgehog inhibitors as a treatment option for individuals diagnosed with metastatic BCC.http://www.odermatol.com/issue-in-html/2022-1-18-metastatic_bcc/
spellingShingle Claire Quigley
Siona Ni Raghallaigh
Metastatic basal cell carcinoma: A report of two cases and a review of the literature
Nasza Dermatologia Online
title Metastatic basal cell carcinoma: A report of two cases and a review of the literature
title_full Metastatic basal cell carcinoma: A report of two cases and a review of the literature
title_fullStr Metastatic basal cell carcinoma: A report of two cases and a review of the literature
title_full_unstemmed Metastatic basal cell carcinoma: A report of two cases and a review of the literature
title_short Metastatic basal cell carcinoma: A report of two cases and a review of the literature
title_sort metastatic basal cell carcinoma a report of two cases and a review of the literature
url http://www.odermatol.com/issue-in-html/2022-1-18-metastatic_bcc/
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AT sionaniraghallaigh metastaticbasalcellcarcinomaareportoftwocasesandareviewoftheliterature