Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis

Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis

Abstract Background Retinal ganglion cells (RGCs) apoptosis is a vital manifestation of retinal ischemia/reperfusion (I/R) injury, yet the underlying mechanisms are not well understood. The contribution of long noncoding RNAs (lncRNAs) to this cellular process is currently being explored. Based on a...

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Bibliographic Details
Main Authors: Yuqing Feng, Jinfang Lu, Xujun Peng, Yanni Ge, Ran Zhang, Huiling Li
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Molecular Medicine
Subjects:
lncRNA uc007nnj.1
I/R
RGCs
Apoptosis
miR-155-5p
Online Access:https://doi.org/10.1186/s10020-022-00591-5

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