The Molecular Mechanisms of Oleanane Aldehyde-β-enone Cytotoxicity against Doxorubicin-Resistant Cancer Cells
Oleanane aldehyde-β-enone (<b>OA</b>), being the semi-synthetic derivative of the triterpenoid betulin, effectively inhibits the proliferation of HBL-100 and K562 cancer cells (IC<sub>50</sub> 0.47–0.53 µM), as well as the proliferation of their resistant subclones with high...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-7737/12/3/415 |