Subjective and objective financial toxicity among colorectal cancer patients: a systematic review
Abstract Background Colorectal cancer (CRC) is the third most common cancer type worldwide. Colorectal cancer treatment costs vary between countries as it depends on policy factors such as treatment algorithms, availability of treatments and whether the treatment is government-funded. Hence, the obj...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Cancer |
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| Online Access: | https://doi.org/10.1186/s12885-023-11814-1 |
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| author | Meram Azzani Zahir Izuan Azhar Aimi Nadira Mat Ruzlin Chen Xin Wee Ely Zarina Samsudin Sabah Mohammed Al-Harazi Sarah Noman |
| author_facet | Meram Azzani Zahir Izuan Azhar Aimi Nadira Mat Ruzlin Chen Xin Wee Ely Zarina Samsudin Sabah Mohammed Al-Harazi Sarah Noman |
| author_sort | Meram Azzani |
| collection | DOAJ |
| description | Abstract Background Colorectal cancer (CRC) is the third most common cancer type worldwide. Colorectal cancer treatment costs vary between countries as it depends on policy factors such as treatment algorithms, availability of treatments and whether the treatment is government-funded. Hence, the objective of this systematic review is to determine the prevalence and measurements of financial toxicity (FT), including the cost of treatment, among colorectal cancer patients. Methods Medline via PubMed platform, Science Direct, Scopus, and CINAHL databases were searched to find studies that examined CRC FT. There was no limit on the design or setting of the study. Results Out of 819 papers identified through an online search, only 15 papers were included in this review. The majority (n = 12, 80%) were from high-income countries, and none from low-income countries. Few studies (n = 2) reported objective FT denoted by the prevalence of catastrophic health expenditure (CHE), 60% (9 out of 15) reported prevalence of subjective FT, which ranges from 7 to 80%, 40% (6 out of 15) included studies reported cost of CRC management– annual direct medical cost ranges from USD 2045 to 10,772 and indirect medical cost ranges from USD 551 to 795. Conclusions There is a lack of consensus in defining and quantifying financial toxicity hindered the comparability of the results to yield the mean cost of managing CRC. Over and beyond that, information from some low-income countries is missing, limiting global representativeness. |
| first_indexed | 2024-03-08T16:17:27Z |
| format | Article |
| id | doaj.art-8912d78144464cf18f5b38c4bb8722c7 |
| institution | Directory Open Access Journal |
| issn | 1471-2407 |
| language | English |
| last_indexed | 2024-03-08T16:17:27Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj.art-8912d78144464cf18f5b38c4bb8722c72024-01-07T12:30:10ZengBMCBMC Cancer1471-24072024-01-012411810.1186/s12885-023-11814-1Subjective and objective financial toxicity among colorectal cancer patients: a systematic reviewMeram Azzani0Zahir Izuan Azhar1Aimi Nadira Mat Ruzlin2Chen Xin Wee3Ely Zarina Samsudin4Sabah Mohammed Al-Harazi5Sarah Noman6Department of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARADepartment of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARADepartment of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARADepartment of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARADepartment of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARADepartment of Early Clinical Exposure and Professional Personal Development, Faculty of Medicine, MAHSA UniversityDepartment of Community Health, Faculty of Medicine and Health Sciences, Universiti Putra MalaysiaAbstract Background Colorectal cancer (CRC) is the third most common cancer type worldwide. Colorectal cancer treatment costs vary between countries as it depends on policy factors such as treatment algorithms, availability of treatments and whether the treatment is government-funded. Hence, the objective of this systematic review is to determine the prevalence and measurements of financial toxicity (FT), including the cost of treatment, among colorectal cancer patients. Methods Medline via PubMed platform, Science Direct, Scopus, and CINAHL databases were searched to find studies that examined CRC FT. There was no limit on the design or setting of the study. Results Out of 819 papers identified through an online search, only 15 papers were included in this review. The majority (n = 12, 80%) were from high-income countries, and none from low-income countries. Few studies (n = 2) reported objective FT denoted by the prevalence of catastrophic health expenditure (CHE), 60% (9 out of 15) reported prevalence of subjective FT, which ranges from 7 to 80%, 40% (6 out of 15) included studies reported cost of CRC management– annual direct medical cost ranges from USD 2045 to 10,772 and indirect medical cost ranges from USD 551 to 795. Conclusions There is a lack of consensus in defining and quantifying financial toxicity hindered the comparability of the results to yield the mean cost of managing CRC. Over and beyond that, information from some low-income countries is missing, limiting global representativeness.https://doi.org/10.1186/s12885-023-11814-1Direct medical costDirect non-medical costIndirect medical costCatastrophic health expenditurePerceived financial hardship |
| spellingShingle | Meram Azzani Zahir Izuan Azhar Aimi Nadira Mat Ruzlin Chen Xin Wee Ely Zarina Samsudin Sabah Mohammed Al-Harazi Sarah Noman Subjective and objective financial toxicity among colorectal cancer patients: a systematic review BMC Cancer Direct medical cost Direct non-medical cost Indirect medical cost Catastrophic health expenditure Perceived financial hardship |
| title | Subjective and objective financial toxicity among colorectal cancer patients: a systematic review |
| title_full | Subjective and objective financial toxicity among colorectal cancer patients: a systematic review |
| title_fullStr | Subjective and objective financial toxicity among colorectal cancer patients: a systematic review |
| title_full_unstemmed | Subjective and objective financial toxicity among colorectal cancer patients: a systematic review |
| title_short | Subjective and objective financial toxicity among colorectal cancer patients: a systematic review |
| title_sort | subjective and objective financial toxicity among colorectal cancer patients a systematic review |
| topic | Direct medical cost Direct non-medical cost Indirect medical cost Catastrophic health expenditure Perceived financial hardship |
| url | https://doi.org/10.1186/s12885-023-11814-1 |
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